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Article
Comparison of microbial communities and volatile profiles of wines made from mulberry and grape
In this study, three kinds of wines separately made from mulberry (MW), grape (GW), or mulberry/grape (MGW) were developed and their enological parameters, sensory scores, volatile components, and microbiota w...
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Article
Open AccessIdentification of early mild cognitive impairment using multi-modal data and graph convolutional networks
The identification of early mild cognitive impairment (EMCI), which is an early stage of Alzheimer’s disease (AD) and is associated with brain structural and functional changes, is still a challenging task. Re...
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Article
Open AccessLabel-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells
Adipocyte accumulation is a predominant feature of age-related thymic involution, but the mechanisms responsible for thymic adipogenesis remain to be elucidated. The aim of this study was to identify key regul...
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Article
Open AccessDietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals
Bitter taste perception is essential for species with selective food intake, enabling them to avoid unpalatable or toxic items. Previous studies noted a marked variation in the number of TAS2R genes among various...
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Article
Open AccessDifferentiated adaptive evolution, episodic relaxation of selective constraints, and pseudogenization of umami and sweet taste genes TAS1Rs in catarrhine primates
Umami and sweet tastes are two important basic taste perceptions that allow animals to recognize diets with nutritious carbohydrates and proteins, respectively. Until recently, analyses of umami and sweet tast...
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Article
Construction of an engineering strain expressing cry7Ab7 gene cloned from Bacillus thuringiensis
The genotype of Bacillus thuringiensis (Bt) strain GW6 isolated in China was identified, and a novel cry7Ab gene was found based on the results of PCRs using 40 pairs of cry universal primers. The cry7Ab gene was...