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Article
Open AccessImplantation of Adipose-Derived Mesenchymal Stromal Cells (ADSCs)-Lining Prosthetic Graft Promotes Vascular Regeneration in Monkeys and Pigs
Current replacement procedures for stenosis or occluded arteries using prosthetic grafts have serious limitations in clinical applications, particularly, endothelialization of the luminal surface is a long-sta...
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Article
Open AccessGenome-wide identification of GH28 family and insight into its contributions to pod shattering resistance in Brassica napus L.
Rapeseed (Brassica napus L.), accounts for nearly 16% of vegetable oil, is the world’s second produced oilseed. However, pod shattering has caused significant yield loses in rapeseed production, particularly duri...
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Article
Open AccessCorrection: NanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model
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Article
Community of Arbuscular Mycorrhizal Fungi in the Rhizosphere Soils with Different Generations of Hybridized Progeny of Wild Erianthus arundinaceus and Sugarcane
This study aimed to explore the community of arbuscular mycorrhizal fungi (AMF) in the rhizosphere soil with different generations of the hybridized progeny of wild Erianthus arundinaceus and sugarcane. Rhizosphe...
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Article
Open AccessIntegrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae)
Herpetospermum pedunculosum (Ser.) C. B. Clarke is a traditional Chinese herbal medicine that heavily relies on the lignans found in its dried ripe seeds (Herpetospermum caudigerum), which have antioxidant and h...
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Article
Epidemiology, pathogenesis, immune evasion mechanism and vaccine development of porcine Deltacoronavirus
Coronaviruses have been identified as pathogens of gastrointestinal and respiratory diseases in humans and various animal species. In recent years, the global spread of new coronaviruses has had profound influ...
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Article
Design, synthesis and herbicidal activity of novel cyclohexanedione derivations containing pyrazole and pyridine groups as potential HPPD inhibitors
4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27; HPPD) is one of the important target enzymes in the development of herbicides. To discover novel HPPD inhibitors with unique molecular, 39 cyclohexanedione d...
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Article
Relative importance of altitude shifts with plant and microbial diversity to soil multifunctionality in grasslands of north-western China
Above- and belowground biodiversity determines the capacity of ecosystems to provide multiple functions simultaneously (i.e., multifunctionality), while their relative importance along environmental gradients ...
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Article
Open AccessNanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model
Nanobodies, also known as VHH or single-domain antibodies, are unique antibody fragments derived solely from heavy chains. They offer advantages of small molecules and conventional antibodies, making them prom...
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Article
Development of a loop-mediated isothermal amplification assay for rapid and sensitive detection of Hemileia vastatrix in coffee plantations
Coffee leaf rust (CLR) caused by Hemileia vastatrix is a devastating worldwide disease. Early monitoring is crucial for controlling CLR quickly and efficiently. However, accurately identifying CLR in its early st...
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Article
The Community of Arbuscular Mycorrhizal Fungi in Sugarcane Rhizosphere Soils in Guangxi, China
In order to analyze the community of the arbuscular mycorrhizal fungi (AMF) in the rhizosphere soil and roots of sugarcane in Guangxi, China, this study analyzed the 18S rDNA gene sequences, soil physicochemic...
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Article
Open AccessEngineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice
Probiotic supplements are suggested to promote human health by preventing pathogen colonization. However, the mechanistic bases for their efficacy in vivo are largely uncharacterized. Here using metabolomics a...
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Article
Open AccessGenome-wide characterization of SDR gene family and its potential role in seed dormancy of Brassica napus L.
Rapeseed (Brassica napus L.) with short or no dormancy period are easy to germinate before harvest (pre-harvest sprouting, PHS). PHS has seriously decreased seed weight and oil content in B. napus. Short-chain de...
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Article
Shifted plant composition predominantly controls nitrogen addition effect on community-level leaf nutrient resorption in a boreal peatland
Leaf nutrient resorption process is an indispensable aspect of plant nutrient utilization strategies in boreal peatlands. However, how nitrogen (N) enrichment alters leaf nutrient resorption is unclear at both...
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Article
Chemotactic rhizocompetence is strengthened by efficient adaptational methylation modification of the 1-aminocyclopropane-1-carboxylic acid chemoreceptor in Pseudomonas sp. UW4
Intensifying chemotactic rhizocompetence is an effective approach to improving PGPR colonization in the plant rhizosphere and promoting plant growth. Whether increasing the efficient adaptational methylation m...
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Article
PABPN1 functions as a predictive biomarker in colorectal carcinoma
PABPN1 acts as a modulator of poly(A) tail length and alternative polyadenylation. This research was aimed to explore the role of PABPN1 in colorectal cancer (CRC).
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Article
Open AccessMuscone inhibits angiotensin II–induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways
Muscone is a chemical monomer derived from musk. Although many studies have confirmed the cardioprotective effects of muscone, the effects of muscone on cardiac hypertrophy and its potential mechanisms are unc...
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Article
Open AccessGBDT_KgluSite: An improved computational prediction model for lysine glutarylation sites based on feature fusion and GBDT classifier
Lysine glutarylation (Kglu) is one of the most important Post-translational modifications (PTMs), which plays significant roles in various cellular functions, including metabolism, mitochondrial processes, and...
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Article
Effects of Mixed Crop** on Sugarcane Growth and the Community of Arbuscular Mycorrhizal Fungi
To explore the effects of mixed crop** of different sugarcane varieties on the growth of sugarcane and the community structure of arbuscular mycorrhizal fungi (AMF), field experiments were conducted using RO...
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Article
Open AccessLysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS
Lysophosphatidic acid (LPA) is an active phospholipid signaling molecule that binds to six specific G protein-coupled receptors (LPA1-6) on the cell surface and exerts a variety of biological functions, including...
