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Article
A New 1,6-Seco-Norisoprenoid from the Leaves and Twigs of Croton yanhuii
A new 1,6-seco-norisoprenoid, named croyanhuin G (1), together with ten known norisoprenoids (2–11), was isolated from the leaves and twigs of Croton yanhuii Y. T. Chang (Euphorbiaceae). The structure of this new...
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Article
Open AccessPorcine lung tissue slices: a culture model for PRCV infection and innate immune response investigations
Respiratory coronaviruses (RCoVs) significantly threaten human health, necessitating the development of an ex vivo respiratory culture system for investigating RCoVs infection. Here, we successfully generated ...
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Article
Enhanced mechanical properties of TZM joint brazed at high temperature using Mo-Ni filler metal with Boron addition
Controlling the growth of brittle intermetallic compounds (IMCs) and interfacial structure is crucial to obtaining desirable mechanical properties of the high-temperature brazing joints of titanium-zirconium-m...
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Article
Machining accuracy reliability optimization of three-axis CNC machine tools using doubly-weighted vector projection response surface method
The reasonable allocation of geometric errors of machine tools can improve their machining accuracy reliability (MAR). However, due to the complexity and high nonlinearity of limit state function (LSF) of MAR,...
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Article
Decolorization of rhodamine B using an ultrasonic oxygen-doped carbon felt as cathode in electro-Fenton system
The inertness of carbon felt as cathode is still one of the challenges encountered in the degradation of pollutants by electro-Fenton. In this study, we used a simple ultrasonic oxidation method to introduce o...
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Article
Effects of the Extrusion Ratio on the Microstructure and Mechanical Properties of Columnar Network Structured TiBw/TA15 Composites
Novel columnar network structure TiB whisker-reinforced TA15 titanium alloy matrix composites (TiBw/TA15 composites) were successfully prepared by low-energy ball milling and subsequent powder compact extrusio...
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Article
Research trends and prospects for hydrogen production from sludge fermentation: based on bibliometric analysis
There are many applications for the technology of producing hydrogen from organic waste. Due to its large volume, high organic content, and stable source, sewage sludge has gained significant attention among v...
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Article
Open AccessP2X7 receptor: a potential target for treating comorbid anxiety and depression
In clinical practice, depression and anxiety frequently coexist, and they are both comorbid with somatic diseases. The P2X7R is an adenosine 5’-triphosphate (ATP)-gated non-selective cation channel that is wid...
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Article
Preparation of crab-shell-based N, O co-doped graded porous carbon for supercapacitors using the confined nanospace deposition method
Biomass-based carbon materials with hierarchical porous structures have attracted attention for their ability to provide more channels and shorten ion transport paths. Here, we developed a simple method based ...
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Article
Thermal Failure Analysis of Gear Transmission System
With its advantages of high transmission accuracy, dependable operation and high efficiency, gear transmission is the most significant and widely used type of mechanical transmission. It is used extensively in...
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Article
Ubiquitin specific peptidase 38 epigenetically regulates KLF transcription factor 5 to augment malignant progression of lung adenocarcinoma
Protein ubiquitination is a common post-translational modification and a critical mechanism for regulating protein stability. This study aimed to explore the role and potential molecular mechanism of ubiquitin...
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Article
Death-associated protein 3 in cell death and beyond
Death-associated protein 3 (DAP3) is a highly conserved guanosine triphosphate (GTP) binding protein. As a component of the mitochondrial ribosome 28 S small subunit, DAP3 is involved in apoptosis pathways and...
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Article
Open AccessThe impact of preoperative biliary drainage on postoperative healthcare-associated infections and clinical outcomes following pancreaticoduodenectomy: a ten-year retrospective analysis
Pancreaticoduodenectomy (PD) is a complex procedure and easily accompanied by healthcare-associated infections (HAIs). This study aimed to assess the impact of PBD on postoperative infections and clinical outc...
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Article
Open AccessConstruction of a nomogram model for deep vein thrombosis in patients with tibial plateau fracture based on the Systemic Inflammatory Response Index
In recent years, the incidence of tibial plateau fracture has been on the rise, predominantly affecting the elderly population. Deep vein thrombosis may lead to poor prognosis in patients. the Systemic Inflamm...
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Article
Protective Effect of Silibinin on Lipopolysaccharide-Induced Endotoxemia by Inhibiting Caspase-11-Dependent Cell Pyroptosis
To explore the protective effect and the underlying mechanism of silibinin (SIB), one of the active compounds from Silybum marianum (L.) Gaertn in endotoxemia.
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Article
Enhancing Fat Transplantation Efficiency in a Mouse Model through Pretreatment of Adipose-Derived Stem Cells with RIP3 Inhibitors
Autologous fat transplantation, widely used in cosmetic and reparative surgery for volumetric enhancements, faces challenges with its inconsistent long-term survival rates. The technique’s efficacy, crucial fo...
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Article
Open AccessKdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair
Cellular senescence assumes pivotal roles in various diseases through the secretion of proinflammatory factors. Despite extensive investigations into vascular senescence associated with aging and degenerative ...
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Article
Open AccessAuthor Correction: Studying the impact of marital status on diagnosis and survival prediction in pancreatic ductal carcinoma using machine learning methods
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Article
Effects of TiB Volume Fraction on the Microstructure and Mechanical Properties of TiBw/TA15 Composites with Novel Columnar Structure
To solve the problem of the inability to obtain plasticity and strength simultaneously in TMCs prepared through traditional powder metallurgy methods, TiBw/TA15 composites with columnar structure were designed...
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Article
zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function
CD80 is a transmembrane glycoprotein belonging to the B7 family, which has emerged as a crucial molecule in T cell modulation via the CD28 or CTLA4 axes. CD80-involved regulation of immune balance is a finely ...
