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Article
Prompt Tuning in Biomedical Relation Extraction
Biomedical relation extraction (RE) is critical in constructing high-quality knowledge graphs and databases as well as supporting many downstream text mining applications. This paper explores prompt tuning on ...
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Article
Regional Adversarial Training for Better Robust Generalization
Adversarial training (AT) has been demonstrated as one of the most promising defense methods against various adversarial attacks. To our knowledge, existing AT-based methods usually train with the locally most...
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Article
Detection of Bubble Flow by Cluster Analysis of Ultrasound Waves’ Spectral Properties
As a non-invasive tool, ultrasound waves can be applied to probe gaseous content of the drilling fluid in offshore oil-drilling operations. The approach is believed to improve sensitivity and accuracy of a gas...
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Article
Preparation of crab-shell-based N, O co-doped graded porous carbon for supercapacitors using the confined nanospace deposition method
Biomass-based carbon materials with hierarchical porous structures have attracted attention for their ability to provide more channels and shorten ion transport paths. Here, we developed a simple method based ...
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Article
Open AccessNCAPH serves as a prognostic factor and promotes the tumor progression in glioma through PI3K/AKT signaling pathway
Non-SMC (Structural Maintenance of Chromosomes) condensin I complex subunit H (NCAPH) has been shown to facilitate progression and predict adverse prognostic outcome in many cancer types. However, the function...
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Article
Surface topography and site stratigraphy effects on the characteristic parameters of design response spectra
Slopes have a significant impact on the ground motion characteristics, which can aggravate the damage degree of building structures during a strong earthquake. However, many studies have focused on the design ...
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Article
Open AccessRegulatory mechanisms of autophagy on DHA and carotenoid accumulation in Crypthecodinium sp. SUN
Autophagy is a crucial process of cellular self-destruction and component reutilization that can affect the accumulation of total fatty acids (TFAs) and carotenoids in microalgae. The regulatory effects of aut...
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Article
Glabridin reduces neuroinflammation by modulating inflammatory signals in LPS-induced in vitro and in vivo models
Chronic neuroinflammation has become one of the important causes of common neurodegeneration disease. Therefore, the target of this study was to explore the protective action of glabridin on lipopolysaccharide...
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Article
Comparison of antioxidant capacity and immune response between low salinity tolerant hybrid and normal variety of Pacific white shrimp (Litopenaeus vannamei)
The Pacific white shrimp (Litopenaeus vannamei) is an economically important aquaculture species worldwide. Antioxidant immune performance is an important indicator of healthy growth and physiology of aquatic org...
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Article
Recent advances in chemical protein synthesis: method developments and biological applications
The central dogma of modern biology underscores the pivotal roles proteins play in diverse biological processes, the study of which necessitates advanced methods to produce proteins with precision and versatil...
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Article
Early impact of albuminuria on cardiac function in patients with chronic kidney disease: a prospective study
Cardiovascular disease (CVD) is the leading cause of end-stage mortality in chronic kidney disease (CKD) patients. However, CVD and CKD are inextricably linked, as microalbuminuria is an independent risk facto...
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Article
Open AccessCharacterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models
Poliovirus receptor-related immunoglobulin domain-containing protein, or PVRIG, is a newly discovered immune checkpoint that has emerged as a promising target for cancer immunotherapy. It is primarily expresse...
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Article
Open AccessDevelopment and validation of predictive models for myopia onset and progression using extensive 15-year refractive data in children and adolescents
Global myopia prevalence poses a substantial public health burden with vision-threatening complications, necessitating effective prevention and control strategies. Precise prediction of spherical equivalent (S...
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Article
Open AccessFemale university students’ fertility intentions and their psychosocial factors
Raising the birth rate can effectively increase the resulting labour supply and minimise the adverse impact of an ageing population on high-quality economic development since the demographic dividend is rapidl...
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Article
Investigating the Mechanical Responses and Construction Optimization for Shallow Super-Large Span Tunnels in Weathered Tuff Stratum Based on Field Monitoring and Flac3D Modeling
To investigate the mechanical responses and construction optimization of shallow super-large span (SLS) tunnels in weathered tuff stratum, the field monitoring scheme and the refined three-dimensional numerica...
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Article
Open AccessId2 epigenetically controls CD8+ T-cell exhaustion by disrupting the assembly of the Tcf3-LSD1 complex
CD8+ T-cell exhaustion is a state of dysfunction that promotes tumor progression and is marked by the generation of Slamf6+ progenitor exhausted (Texprog) and Tim-3+ terminally exhausted (Texterm) subpopulations....
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Article
Open AccessThe combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway
Astragaloside IV (As-IV) and Tanshinone IIA (Ta-IIA) are the main ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and Salvia miltiorrhiza Bunge, respectively, both of which hav...
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Article
Use of The Rubbing Grid Paper for Injection Guidance in Botulinum Toxin A Treatment of Hyperhidrosis
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Article
Open AccessA multicenter clinical AI system study for detection and diagnosis of focal liver lesions
Early and accurate diagnosis of focal liver lesions is crucial for effective treatment and prognosis. We developed and validated a fully automated diagnostic system named Liver Artificial Intelligence Diagnosi...
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Article
Open AccessDiscovering Cathodic Biocompatibility for Aqueous Zn–MnO2 Battery: An Integrating Biomass Carbon Strategy
γ-MnO2 loaded on N-doped biomass carbon from grapefruit peel is firstly developed.
The splendid cathodic properties (e.g., c...
