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Article
Effect of Cerium Element on Non-metallic Inclusions Formation During Molten and Solidification Processes of Q355 Microalloy Structural Steel
50~690 ppm cerium-containing steel samples were prepared in a 50 kg vacuum induction furnace. The morphology, composition, and size of rare-earth inclusions in steel with different cerium contents were charact...
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Article
Disulfiram/Copper Activates ER Stress to Promote Immunogenic Cell Death of Oral Squamous Cell Carcinoma
Disulfiram/copper complex (DSF/Cu) was found to have anti-tumor effects in a range of malignancies, including oral squamous cell carcinoma (OSCC), yet its precise mechanism remains unknown. It has been shown t...
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Article
Open AccessLarge-scale annotated dataset for cochlear hair cell detection and classification
Our sense of hearing is mediated by cochlear hair cells, of which there are two types organized in one row of inner hair cells and three rows of outer hair cells. Each cochlea contains 5–15 thousand terminally...
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Article
Open AccessExploring COVID-19 Phobia among International Chinese College Students in South Korea Before Ending COVID-19 Restrictions
College students, considered to be the driving force of society, are highly vulnerable to COVID-19. At a time when facing a new pandemic wave in 2022, China’s policy was in contrast with that of Korea. We inve...
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Article
Open AccessSpindle component 25 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis
Spindle component 25 (SPC25) is one of the four proteins that make up the nuclear division cycle 80 (NDC80) complex, the other three components being Ndc80p, Nuf2p, and spindle component 24. Deregulation of th...
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Article
Strategic enterprise management in the age of energy transition: a roadmap for sustainable business practices
China's rapid economic growth in recent years has raised concerns about resource utilization and environmental sustainability. This study aims to assess the efficiency landscape of China's sectors between 2015...
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Article
Open AccessManufacturing, quality control, and GLP-grade preclinical study of nebulized allogenic adipose mesenchymal stromal cells-derived extracellular vesicles
Human adipose stromal cells-derived extracellular vesicles (haMSC-EVs) have been shown to alleviate inflammation in acute lung injury (ALI) animal models. However, there are few systemic studies on clinical-gr...
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Article
Open AccessData-efficient model-based reinforcement learning with trajectory discrimination
Deep reinforcement learning has always been used to solve high-dimensional complex sequential decision problems. However, one of the biggest challenges for reinforcement learning is sample efficiency, especial...
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Article
Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis
Abnormal accumulation of senescent cells in tissues has been shown to facilitate the onset and progression of various diseases. As an important protein involving in the regulation of cellular senescence proces...
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Article
Open AccessA comparative study of mono-exponential and advanced diffusion-weighted imaging in differentiating stage IA endometrial carcinoma from benign endometrial lesions
The purpose of the current investigation is to compare the efficacy of different diffusion models and diffusion kurtosis imaging (DKI) in differentiating stage IA endometrial carcinoma (IAEC) from benign endom...
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Article
Open AccessShared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome
There are two major genetic types of Epstein-Barr Virus (EBV): type 1 (EBV-1) and type 2 (EBV-2). EBV functions by manipulating gene expression in host B cells, using virus-encoded gene regulatory proteins inc...
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Article
Refiner: a general object position refinement algorithm for visual tracking
Object tracking is an important topic in computer vision. Most existing trackers require an accurate initial position of the target. However, in the real application, the initial location for tracking may not ...
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Article
Mechanism and experimental evaluation on surface morphology of GCr15SiMn with ultrasonic vibration grinding
GCr15SiMn is a kind of bearing steel material with good physical and mechanical properties, which is broadly used in aerospace, automotive, and other advanced manufacturing fields. However, the harsh environme...
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Article
Promotion Effect of Microwave-Assisted Prepared Porous Fe–Mn Catalyst on Toluene Removal
Fe–Mn oxide is widely used for VOCs catalytic oxidation due to its advantages of low cost and easy availability. However, the low-temperature catalytic oxidation activity of Fe–Mn oxide is limited. In order to...
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Article
Machinability of SiCf/SiC ceramic matrix composites using longitudinal-torsional coupled rotary ultrasonic machining
SiCf/SiC ceramic matrix composites are widely used in high-tech fields such as aerospace and usually processed by grinding methods. In the conventional machining (CON-M), the cutting force during machining is inc...
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Article
Two-dimensional ultrasonic vibration-assisted dry grinding gear: grinding force and surface characteristics
Ultrasonic vibration-assisted dry grinding has been focused on to alleviate the cutting fluids' negative impact on environment, avoid the unnecessary waste, and reduce the manufacturing costs. However, this te...
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Article
Study on the influence of ultrasonic-assisted cutting on the surface quality of CFRP
In order to study the influence of machining methods and parameters on the surface quality of carbon fiber reinforced composites (CFRP) in the cutting process, the finite element simulation model of ultrasonic...
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Article
Open AccessSingle-cell RNA sequencing of cervical exfoliated cells reveals potential biomarkers and cellular pathogenesis in cervical carcinogenesis
Cervical cancer (CC) is a common gynecological malignancy. Despite the current screening methods have been proved effectively and significantly decreased CC morbidity and mortality, deficiencies still exist. S...
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Article
TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation
Sterile inflammation, also known as ‘inflammaging’, is a hallmark of tissue aging. Cellular senescence contributes to tissue aging, in part, through the secretion of proinflammatory factors collectively known ...
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Article
Open AccessAsymmetric adhesive SIS-based wound dressings for therapeutically targeting wound repair
Severe tissue injuries pose a significant risk to human health. Conventional wound dressings fall short in achieving effective tissue regeneration, resulting in suboptimal postoperative healing outcomes. In th...
