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    Article

    In Situ Assembly of Melittin-PHA Microspheres for Enhancing Therapeutic Efficacy in Cancer Treatment

    Amphiphilic cationic peptide (ACP) is a widely studied biofilm-active peptide that has great potential in cancer treatment. However, poor stability, a short half-life, and complex preparation pose significant ...

    Xueyu Fan, Chao Zhang, Shuangqing Fu in International Journal of Peptide Research … (2024)

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    Application of PHA surface binding proteins of alkali-tolerant Bacillus as surfactants

    Amphiphilic protein has lipophilic and hydrophilic domains, displaying the potential for development as a biosurfactant. The polyhydroxyalkanoate (PHA) surface binding protein derived from Bacillus is a type of p...

    Xueyu Fan, Shuangqing Fu, Junpo Jiang, Dexu Liu in Brazilian Journal of Microbiology (2024)

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    Article

    Enhanced Production of Iturin A-2 Generated from Bacillus velezensis T701 and the Antitumor Activity of Iturin A-2 against Human Gastric Carcinoma Cells

    Bacillus velezensis T701 was used to produce lipopeptide. Among the lipopeptide, iturin A-2 was of the highest antitumor activity. In order to get higher yield of iturin A-2, the fermentation conditions of strain...

    Junpo Jiang, Mengnan Han, Shuangqing Fu in International Journal of Peptide Research … (2021)