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Article
Unraveling Effects of AI Chatbots on EFL Learners’ Language Skill Development: A Meta-analysis
While empirical investigations of artificial intelligence (AI) chatbots for English-as-a-foreign-language (EFL) learners’ language skill development have been receiving considerable attention, a quantitative a...
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Article
Open AccessPrediction models for postoperative recurrence of non-lactating mastitis based on machine learning
This study aims to build a machine learning (ML) model to predict the recurrence probability for postoperative non-lactating mastitis (NLM) by Random Forest (RF) and XGBoost algorithms. It can provide the abil...
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Article
Open AccesscircEPB41L2 blocks the progression and metastasis in non-small cell lung cancer by promoting TRIP12-triggered PTBP1 ubiquitylation
The metastasis of non-small cell lung cancer (NSCLC) is the leading death cause of NSCLC patients, which requires new biomarkers for precise diagnosis and treatment. Circular RNAs (circRNAs), the novel noncodi...
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Article
Open AccessEffects of dynamic and rigid implantation on biomechanical characteristics of different sagittal alignment lumbar after single- or double-level spinal fixations: a finite-element modeling study
Although it is critical to understand the accelerated degeneration of adjacent segments after fusion, the biomechanical properties of the spine have not been thoroughly studied after various fusion techniques....
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Article
Open AccessThe predictive value of uterine artery Doppler in the success rate of pregnancy from the first frozen embryo transfer during the implantation window
Worldwide, frozen embryo transfer (FET) has become a new strategy for the treatment of infertility. The success of FET is closely related to endometrial receptivity. Does uterine artery Doppler during the impl...
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Article
Open AccessLimited protection of pneumococcal vaccines against emergent Streptococcus pneumoniae serotype 14/ST876 strains
Streptococcus pneumoniae (Spn) is a major cause of child death. We investigated the epidemiology of S. pneumoniae in a pediatric fever clinic and explored the genomics basis of the limited vaccine response of ser...
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Article
Open AccessLC/MS-based untargeted lipidomics reveals lipid signatures of nonpuerperal mastitis
Nonpuerperal mastitis (NPM) is a disease that presents with redness, swelling, heat, and pain during nonlactation and can often be confused with breast cancer. The etiology of NPM remains elusive; however, eme...
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Article
NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway
Trophoblasts are the most important parts of the placenta in early pregnancy. Trophoblast cell dysfunction can induce embryo implantation insufficiency, thereby resulting in multiple diseases, including recurr...
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Article
Open AccessPseudomonas aeruginosa biofilm dispersion by the mouse antimicrobial peptide CRAMP
Pseudomonas aeruginosa (P. aeruginosa) is a known bacterium that produces biofilms and causes severe infection. Furthermore, P. aeruginosa biofilms are extremely difficult to eradicate, leading to the developmen...
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Article
Quantum chemical studies to functionalization of boron nitride nanotube (BNNT) as effective nanocarriers
Aniline molecule was used to modify the surface of a boron nitride nanotube (BNNT), and the effect of aniline surface modification on main electronic, structural, and energy properties was investigated by perf...
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Article
A study of BERT for context-aware neural machine translation
Context-aware neural machine translation (NMT), which targets at translating sentences with contextual information, has attracted much attention recently. A key problem for context-aware NMT is to effectively ...
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Article
Open AccessUp-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling
MTHFD2 is a folate-coupled metabolic enzyme, which has been proved to participant in the metabolic reprogramming and tumor cell-sustaining proliferative capacity. However, the function of MTHFD2 in the develop...
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Article
Open AccessIncreased expression of KPNA2 predicts unfavorable prognosis in ovarian cancer patients, possibly by targeting KIF4A signaling
Karyopherin α-2 (KPNA2) is a member of karyopherin family, which is proved to be responsible for the import or export of cargo proteins. Studies have determined that KPNA2 is associated with the development an...
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Article
Open AccessTesticular STAC3 regulates Leydig cell steroidogenesis through potentiating mitochondrial membrane potential and StAR processing
SH3 and cysteine-rich protein 3 (STAC3), a small adapter protein originally identified as a core component of excitation–contraction coupling machinery, regulates the voltage-induced Ca2+ release in skeletal musc...
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Article
Open AccessRare heterotopic pregnancy after frozen embryo transfer: a case report and literature review
Heterotopic pregnancy occurred after frozen embryo transfer with two D3 embryos, and the case had a history of bilateral sal**ectomy due to sal**ocyesis. An ectopic heterotopic pregnancy was implanted in t...
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Article
How do Cats Resist Landing Injury: Insights into the Multi-level Buffering Mechanism
When humans jump down from a high position, there is a risk of serious injury to the lower limbs. However, cats can jump down from the same heights without any injury because of their excellent ability to atte...
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Article
Open AccessMenstrual characteristics, disorders and associated risk factors among female international students in Zhejiang Province, China: a cross-sectional survey
Until now, no previous study has addressed the menstrual patterns among female international students in China. In this present study, our objectives are to ascertain the menstrual characteristics and address ...
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Article
Open AccessMaternal high-fat diet impairs follicular development of offspring through intraovarian kisspeptin/GPR54 system
Excessive gestational weight gain (GWG), which is associated with adverse long-term effects on the health of the offspring, has become a major clinical problem. Accumulating evidence indicates that the ovary k...
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Article
Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey
Ovarian aging is closely tied to the decline in ovarian follicular reserve and oocyte quality. During the prolonged reproductive lifespan of the female, granulosa cells connected with oocytes play critical rol...
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Article
Open AccessHigh-fat diet decreases the expression of Kiss1 mRNA and kisspeptin in the ovary, and increases ovulatory dysfunction in postpubertal female rats
Female reproductive health is noticeably compromised by obesity. The underlying mechanisms remain to be elucidated. Accumulating evidence indicates that the expression level of ovarian Kiss1 peaks in the afternoo...