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  1. Article

    Open Access

    ATF3 coordinates the survival and proliferation of cardiac macrophages and protects against ischemia–reperfusion injury

    Cardiac resident MerTK+ macrophages exert multiple protective roles after ischemic injury; however, the mechanisms regulating their fate are not fully understood. In the present study, we show that the GAS6-induc...

    Yihui Shao, Yang Li, Yan Liu, Shuolin Zhu, Jianing Wu… in Nature Cardiovascular Research (2024)

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    Article

    FABP5 Deficiency Impairs Mitochondrial Function and Aggravates Pathological Cardiac Remodeling and Dysfunction

    Fatty acid-binding protein 5 (FABP5) is an important member of the FABP family and plays a vital role in the metabolism of fatty acids. However, few studies have examined the role of FABP5 in pathological card...

    Shanquan Gao, Guoqi Li, Yihui Shao, Zhipeng Wei, Shan Huang… in Cardiovascular Toxicology (2021)

  3. No Access

    Article

    Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction

    Vascular smooth muscle cells (VSMCs) shift from a physiological contractile phenotype to an adverse proliferative or synthetic state, which is a major event leading to aortic disease. VSMCs are exposed to mult...

    Yihui Shao, Guoqi Li, Shan Huang, Zhenfeng Li, Bokang Qiao… in Cardiovascular Toxicology (2020)