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Article
Open AccessCelastrol ameliorates hypoxic-ischemic brain injury in neonatal rats by reducing oxidative stress and inflammation
Hypoxic-ischemic encephalopathy (HIE) is caused by perinatal hypoxia and subsequent reductions in cerebral blood flow and is one of the leading causes of severe disability or death in newborns. Despite its pre...
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Article
The role of exogenous hydrogen sulfide in mitigating cadmium toxicity in plants: A comprehensive meta-analysis
Reducing the accumulation of cadmium (Cd) and mitigating its toxicity are pivotal strategies for addressing Cd pollution’s threats to agriculture and human health. Hydrogen sulfide (H2S) serves as a signaling mol...
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Article
Open AccessPredictors of mortality and poor outcome for patients with severe infectious encephalitis in the intensive care unit: a cross-sectional study
There are few thorough studies assessing predictors of severe encephalitis, despite the poor prognosis and high mortality associated with severe encephalitis. The study aims to evaluate the clinical predictors...
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Article
Open AccessQuantum image representations based on density matrices in open quantum systems
So far, research on quantum image representation has gone through more than 20 years. During this time, the quantum image representation models used have almost all been based on state vectors. However, in pra...
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Article
Histogram algorithm and its circuit design based on parallel computing for quantum video
Quantum image histogram as a preprocessing result in quantum image processing contains the gray information of the image and plays an important role in subsequent image processing. As far as we know, there are...
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Article
Investigation of metabolite alterations in the kidneys of methionine-choline-deficient mouse by mass spectrometry imaging
Methionine and choline both are essential nutrients which are needed for methyl group metabolism. A methionine-choline-deficient (MCD) diet leads to pathological changes in the kidney. The mechanism of the MCD...
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Article
Open AccessReducing pediatric total-body PET/CT imaging scan time with multimodal artificial intelligence technology
This study aims to decrease the scan time and enhance image quality in pediatric total-body PET imaging by utilizing multimodal artificial intelligence techniques.
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Article
Patlak-Ki derived from ultra-high sensitivity dynamic total body [18F]FDG PET/CT correlates with the response to induction immuno-chemotherapy in locally advanced non-small cell lung cancer patients
This study aimed to investigate the predictive value of metabolic features in response to induction immuno-chemotherapy in patients with locally advanced non-small cell cancer (LA-NSCLC), using ultra-high sens...
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Article
PET/CT scan without sedation: how to use total-body PET/CT to salvage child’s involuntary movement?
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Article
Benzyl isocyanate: an effective high-voltage film-forming additive for lithium-ion batteries
The advancement of high-energy density lithium-ion batteries has an important impact on develo** and popularizing electric vehicles, drones, and other electric tools. However, inferior interfacial stability ...
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Article
Open AccessUtilization of five data mining algorithms combined with simplified preprocessing to establish reference intervals of thyroid-related hormones for non-elderly adults
Despite the extensive research on data mining algorithms, there is still a lack of a standard protocol to evaluate the performance of the existing algorithms. Therefore, the study aims to provide a novel proce...
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Article
Open AccessGenome-Wide Effects on Gene Expression Between Parental and Filial Generations of Trisomy 11 and 12 of Rice
Aneuploid refers to the gene dosage imbalance due to copy number alterations. Aneuploidy is generally harmful to the growth, development and reproduction of organisms according to the numerous research. Howeve...
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Article
Significant CT dose reduction of 2-[18F]FDG PET/CT in pretreatment pediatric lymphoma without compromising the diagnostic and staging efficacy
To compare the diagnostic and staging efficacy of PET/diagnostic-level CT (PET/DxCT) and PET/low-dose CT (PET/LDCT) in pretreatment pediatric lymphoma patients and to estimate the reduction of the CT effective...
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Article
Open AccessDrugRepo: a novel approach to repurposing drugs based on chemical and genomic features
The drug development process consumes 9–12 years and approximately one billion US dollars in costs. Due to the high finances and time costs required by the traditional drug discovery paradigm, repurposing old ...
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Article
Full-length versus intact PTH concentrations in pseudohypoparathyroidism type 1 and primary hyperparathyroidism: clinical evaluation of immunoassays in individuals from China
The application of the third-generation parathyroid hormone (PTH) assay [PTH(1–84) assay] for evaluating PTH levels in patients with pseudohypoparathyroidism type-1 (PHP1) is less popular than the second-gener...
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Article
Hes1 Controls Proliferation and Apoptosis in Chronic Lymphoblastic Leukemia Cells by Modulating PTEN Expression
Hairy and enhancer of split homolog-1 (HES1), regulated by the Notch, has been reported to play important roles in the immune response and cancers, such as leukemia. In this study, we aim to explore the effect...
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Open AccessAn innovative approach based on real-world big data mining for calculating the sample size of the reference interval established using transformed parametric and non-parametric methods
Currently, the direct method is the main approach for establishment of reference interval (RI). However, only a handful of studies have described the effects of sample size on establishment of RI and estimatio...
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Article
Preparation and mechanical properties of CNTs/phenolic resin microcapsules
In order to keep the microcapsules intact during transportation and storage, the mechanical properties of the microcapsules need to be enhanced, and therefore, we innovatively attached the oxidized carbon nano...
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Article
Evaluation of pediatric malignancies using total-body PET/CT with half-dose [18F]-FDG
To explore the impact of a true half dose of [18F]-FDG on image quality in pediatric oncological patients undergoing total-body PET/CT and investigate short acquisition times with half-dose injected activity.
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Article
Spatial scale effects of landscape patterns on water quality changes in drinking water source protection areas: a case study in the Guishui River Basin, China
Understanding the correlation between landscape patterns and the water quality of protected drinking water areas is essential for the sustainable use of water and soil resources in watersheds and the environme...
