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Article
Construction of an engineering strain expressing cry7Ab7 gene cloned from Bacillus thuringiensis
The genotype of Bacillus thuringiensis (Bt) strain GW6 isolated in China was identified, and a novel cry7Ab gene was found based on the results of PCRs using 40 pairs of cry universal primers. The cry7Ab gene was...
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Article
Hypermethylation of CpG islands is more prevalent than hypomethylation across the entire genome in breast carcinogenesis
This study aimed to establish a high-throughput, genome-wide and non-gene-specific approach to assess the methylation status of multiple CpG islands in parallel and employ it to detect the CpG island methylati...
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Article
Open AccessDifferentiated adaptive evolution, episodic relaxation of selective constraints, and pseudogenization of umami and sweet taste genes TAS1Rs in catarrhine primates
Umami and sweet tastes are two important basic taste perceptions that allow animals to recognize diets with nutritious carbohydrates and proteins, respectively. Until recently, analyses of umami and sweet tast...
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Chapter and Conference Paper
Sentiment Analysis for Images on Microblogging by Integrating Textual Information with Multiple Kernel Learning
Image is one of the most important means to express users’ emotions on microblogging, like Sina Weibo. More and more people post only images on it, due to the fast and convenient nature of image. Taking a post...
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Article
Open AccessDietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals
Bitter taste perception is essential for species with selective food intake, enabling them to avoid unpalatable or toxic items. Previous studies noted a marked variation in the number of TAS2R genes among various...
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Article
Open AccessTailoring femtosecond 1.5-μm Bessel beams for manufacturing high-aspect-ratio through-silicon vias
Three-dimensional integrated circuits (3D ICs) are an attractive replacement for conventional 2D ICs as high-performance, low-power-consumption, and small-footprint microelectronic devices. However, one of the...
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Article
Extraction of microbial transglutaminase from Amycolatopsis sp. fermentation broth using aqueous two-phase system
Partitioning of microbial transglutaminase (MTG) from Amycolatopsis sp. in the polyethylene glycol (PEG)/salt-based ATPS was investigated for the first time. The key parameters such as the molecular weight of PEG...
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Article
Prostaglandin E2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes
Diabetic retinopathy is a common microvascular complication of diabetes mellitus and is initiated by inflammation and apoptosis-associated retinal endothelial cell damage. Prostaglandin E2 (PGE2) has emerged as a...
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Article
Open AccessLabel-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells
Adipocyte accumulation is a predominant feature of age-related thymic involution, but the mechanisms responsible for thymic adipogenesis remain to be elucidated. The aim of this study was to identify key regul...
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Chapter and Conference Paper
Turn-Level Recurrence Self-attention for Joint Dialogue Action Prediction and Response Generation
In task-oriented dialogue systems, semantically controlled natural language generation is the procedure to generate responses based on current context information. Seq2seq models are widely used to generate di...
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Chapter and Conference Paper
KGWD: Knowledge Graph Based Wide & Deep Framework for Recommendation
Knowledge Graph (KG) contains rich real-world auxiliary information, which can be leveraged to improve the performance of recommender systems. Nevertheless, existing recommender systems usually sample and aggr...
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Article
Open AccessCharacteristics of cognitive impairment in adult asymptomatic moyamoya disease
Cognitive impairment in adult moyamoya disease (MMD) is thought to be the result of ischemic stroke; however, the presence and extent of cognitive decline in asymptomatic patients is unclear.
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Article
Open AccessIdentification of early mild cognitive impairment using multi-modal data and graph convolutional networks
The identification of early mild cognitive impairment (EMCI), which is an early stage of Alzheimer’s disease (AD) and is associated with brain structural and functional changes, is still a challenging task. Re...
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Chapter and Conference Paper
Data Mining and Its Application in Science and Technology E-Government
Improving the ability of independent innovation and building an innovation-oriented country are the core of the national development strategy and also the key to improving the comprehensive national strength ....
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Chapter and Conference Paper
Development Experience and Application of Machine Learning
Machine learning is the foundation of computer intelligence, known as the core of artificial intelligence. Nowadays, the main development direction of information industry such as computer science and artifici...
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Chapter and Conference Paper
Category-Based Strategy-Driven Question Generator for Visual Dialogue
GuessWhat?! is a task-oriented visual dialogue task which has two players, a guesser and an oracle. Guesser aims to locate the object supposed by oracle by asking several Yes/No questions which are answered by...
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Article
Fault diagnosis of discrete-event systems under a general architecture
Diagnosability is an important characteristic indicator to determine whether the system is stable and reliable. In this paper, the general architecture of event-state-combination diagnosability is investigated...
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Article
Intraoperative transit-time ultrasonography combined with FLOW800 predicts the occurrence of cerebral hyperperfusion syndrome after direct revascularization of Moyamoya disease: a preliminary study
Cerebral hyperperfusion syndrome (CHS) is a common complication after direct bypass surgery in patients with Moyamoya disease (MMD). Since preventive measures may be inadequate, we assessed whether the blood f...
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Article
Current attitudes and preconceptions towards expanded carrier screening in the Eastern Chinese reproductive-aged population
A growing number of Chinese individuals of reproductive age will face the choice of accepting or refusing expanded carrier screening (ECS). This study aimed to explore the awareness, wishes, and possible misco...
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Article
Novel Single Primer Isothermal Amplification Method for the Visual Detection of Vibrio parahaemolyticus
As a typical halophilic bacterium, Vibrio parahaemolyticus (V. parahaemolyticus) is regarded as one of the marine seafood-borne pathogens causing severe illnesses in humans and aquatic animals. Herein, a novel si...
