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Article
Robotic-assisted radical resection versus open surgery for cholangiocarcinoma: a systematic review and meta-analysis
To compare the clinical efficacy and safety of robot-assisted resection and open surgery for cholangiocarcinoma (CCA). We conducted a comprehensive search of PubMed, the Cochrane Library, and Embase databases ...
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Article
Open AccessExploring the causes of the prevalence of vancomycin-resistant Enterococcus faecalis
Bacterial drug resistance represents a significant global concern, with vancomycin-resistant Enterococcus faecalis posing a particularly grave threat to contemporary healthcare systems. This study aims to reveal ...
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Article
Overexpressing Bcl-2 enhances murine chimeric antigen receptor T cell therapy against solid tumor
Chimeric antigen receptor T (CART) cell therapy has demonstrated promising potential in the treatment of hematologic malignancies. However, its application to solid tumors is limited due to the restrictive nat...
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Article
Transcription factors in chimeric antigen receptor T-cell development
Chimeric antigen receptor (CAR) T-cell therapy is a new and innovative approach to treating cancers that has shown promising results in the treatment of lymphoma. However, it has been found to be less effectiv...
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Article
Open AccessMetabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer
This study aimed to explore potential indicators associated with the neoadjuvant efficacy of TCbHP regimen (taxane, carboplatin, trastuzumab, and pertuzumab) in HER2 + breast cancer (BrCa) patients.
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Article
Open AccessPhilosophical practice and its development in China: opportunities and challenges
This paper examines the application and evolution of philosophical practice in China, which employs philosophical principles and methods to facilitate insights and address life’s complexities. We aim to bridge...
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Article
Open AccessEffectiveness of WeChat-assisted preoperative education to reduce perioperative anxiety in breast cancer patients: a prospective randomized controlled study protocol
Breast cancer is the most prevalent cancer among women globally, and surgical procedures continue to be the primary treatment. However, over 50% of patients experience preoperative anxiety due to the unknown a...
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Article
Open AccessPopulation-based BRCA germline mutation screening in the Han Chinese identifies individuals at risk of BRCA mutation-related cancer: experience from a clinical diagnostic center from greater Shanghai area
Deleterious BRCA1/2 (BRCA) mutation raises the risk for BRCA mutation-related malignancies, including breast, ovarian, prostate, and pancreatic cancer. Germline variation of BRCA exhibits substantial ethnical div...
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Article
TRIM21-dependent ultrasmall chiral gold nanoparticles for preventing microglia senescence against Alzheimer’s disease
Tripartite motif 21 (TRIM21) is an E3 ubiquitin ligase that shows great promise for protein degradation through ubiquitination. Here, ultrasmall chiral gold nanoparticles (D- or L-NPs) modified by D- or L-glut...
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Article
A comparison of invasive arterial blood pressure measurement with oscillometric non-invasive blood pressure measurement in patients with sepsis
This study aimed to compare non-invasive oscillometric blood pressure (NIBP) measurement with invasive arterial blood pressure (IBP) measurement in patients with sepsis.
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Article
Open AccessLarge-scale analysis of the N-terminal regulatory elements of the kinase domain in plant Receptor-like kinase family
The N-terminal regulatory element (NRE) of Receptor-like kinases (RLKs), consisting of the juxtamembrane segment in receptor kinases (RKs) and the N-terminal extension segment in RLCKs, is a crucial component ...
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Article
Folk Beliefs of Artificial Intelligence and Robots
Artificial intelligence (AI) and robots have the potential to revolutionize society, with impacts ranging from the broadest reaches of industry and policy to the minutiae of daily life. The extent to which AI-...
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Article
Open AccessA nomogram based on peripheral lymphocyte for predicting 8-year survival in patients with prostate cancer: a single-center study using LASSO-cox regression
The purpose of this study was to develop a functional clinical nomogram for predicting 8-year overall survival (OS) of patients with prostate cancer (PCa) primary based on peripheral lymphocyte.
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Article
Open AccessA pan-cancer analysis uncovering the function of CRHBP in tumor immunity, prognosis and drug response: especially its function in LIHC
Corticotropin-releasing hormone-binding protein (CRHBP) is involved in many physiological processes. However, it is still unclear what role CRHBP has in tumor immunity and prognosis prediction. Using databases...
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Article
Open AccessStructural biases in disordered proteins are prevalent in the cell
Intrinsically disordered proteins and protein regions (IDPs) are prevalent in all proteomes and are essential to cellular function. Unlike folded proteins, IDPs exist in an ensemble of dissimilar conformations...
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Article
Audio Mixing Inversion via Embodied Self-supervised Learning
Audio mixing is a crucial part of music production. For analyzing or recreating audio mixing, it is of great importance to conduct research on estimating mixing parameters used to create mixdowns from music recor...
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Article
Open AccessSHC: soft-hard correspondences framework for simplifying point cloud registration
Point cloud registration is a multifaceted problem that involves a series of procedures. Many deep learning methods employ complex structured networks to achieve robust registration performance. However, these...
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Article
Open AccessAn innovative staged prosthetic lengthening reconstruction strategy for osteosarcoma-related leg discrepancy
Correction of leg length discrepancy (LLD) in skeletally mature patients with osteosarcoma was rarely reported and quite challenging. This study aimed to propose a treatment strategy of staged lengthening and ...
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Chapter and Conference Paper
AMCNet: Adaptive Matching Constraint for Unsupervised Point Cloud Registration
The registration of 3D point cloud with numerous applications in robotics, medical imaging and other industries. However, due to the lack of accurate data annotation, the performance of unsupervised point clou...
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Chapter and Conference Paper
AMDNet: Adaptive Fall Detection Based on Multi-scale Deformable Convolution Network
Recent studies by the World Health Organization have shown that human falls have become the leading cause of injury and death worldwide. Therefore, human fall detection is becoming an increasingly important re...
