2,208 Result(s)
-
Article
Correction to: Construction of a New Immune-Related Competing Endogenous RNA Network with Prognostic Value in Lung Adenocarcinoma
-
Article
A Neural-network-based Alternative Scheme to Include Nonhydrostatic Processes in an Atmospheric Dynamical Core
Here, a nonhydrostatic alternative scheme (NAS) is proposed for the grey zone where the nonhydrostatic impact on the atmosphere is evident but not large enough to justify the necessity to include an implicit n...
-
Article
Combining serum microRNAs and machine learning algorithms for diagnosing infectious fever after HSCT
Infection post-hematopoietic stem cell transplantation (HSCT) is one of the main causes of patient mortality. Fever is the most crucial clinical symptom indicating infection. However, current microbial detecti...
-
Article
The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability
Licorice flavonoids (LFs) are derived from perennial herb licorice and have been attaining a considerable interest in cosmetic and skin ailment treatments. However, some LFs compounds exhibited poor permeation...
-
Article
A New 1,6-Seco-Norisoprenoid from the Leaves and Twigs of Croton yanhuii
A new 1,6-seco-norisoprenoid, named croyanhuin G (1), together with ten known norisoprenoids (2–11), was isolated from the leaves and twigs of Croton yanhuii Y. T. Chang (Euphorbiaceae). The structure of this new...
-
Article
Open AccessDisease burden of mental disorders among children and adolescents considering both co-morbidities and suicide in Northeastern China
Few studies have assessed the burden of mental disorders among children and adolescents considering the impact of co-morbidities and suicide on disability adjusted life years (DALYs).
-
Article
Open AccessRisk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database
Medullary Carcinoma of the Colon (MCC) is a rare histological subtype of colon cancer, and there is currently no recognized optimal treatment plan for it, with its prognosis remaining unclear. The aim of this ...
-
Article
Fluoride Induces Neurocytotoxicity by Disrupting Lysosomal Iron Metabolism and Membrane Permeability
The detrimental effects of fluoride on neurotoxicity have been widely recorded, yet the detailed mechanisms underlying these effects remain unclear. This study explores lysosomal iron metabolism in fluoride-re...
-
Article
Open AccessCorrection: Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system
-
Article
Multi-scale Lesion Feature Fusion and Location-Aware for Chest Multi-disease Detection
Accurately identifying and locating lesions in chest X-rays has the potential to significantly enhance diagnostic efficiency, quality, and interpretability. However, current methods primarily focus on detectin...
-
Article
Open AccessRisk factors for malnutrition in patients with diabetic foot ulcer and its association with prolonged length of hospitalization
The study was designed to investigate the occurrence and risk factors of malnutrition in diabetic foot ulcers (DFU) patients and examine the association between malnutrition and length of stay (LOS).
-
Article
Correction for: Cornel iridoid glycoside exerts a neuroprotective effect on neuroinflammation in rats with brain injury by inhibiting NF-kB and STAT3
-
Article
Open AccessClinical and genetic analysis of methylmalonic aciduria in 60 patients from Southern China: a single center retrospective study
Methylmalonic aciduria (MMA) is a group of rare genetic metabolic disorders resulting from defects in methylmalonyl coenzyme A mutase (MCM) or intracellular cobalamin (cbl) metabolism. MMA patients show divers...
-
Article
Open AccessEfficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study
Chimeric antigen receptor T (CAR-T) cells have been proposed for HIV-1 treatment but have not yet demonstrated desirable therapeutic efficacy. Here, we report newly developed anti-HIV-1 CAR-T cells armed with ...
-
Article
Open AccessEfficacy of ganglion impar block combined with pudendal nerve pulsed radiofrequency for pudendal neuralgia management—a randomized clinical trial
Pudendal neuralgia is a chronic and debilitating condition. Its prevalence ranges from 5 to 26%. Currently, therapeutic approaches to treat pudendal neuralgia include patient education, medication management, ...
-
Article
FBXO11 variants are associated with intellectual disability and variable clinical manifestation in Chinese affected individuals
F-box protein 11 (FBXO11) is a member of F-Box protein family, which has recently been proved to be associated with intellectual developmental disorder with dysmorphic facies and behavioral abnormalities (IDDFBA,...
-
Article
Improvement of sulfide stress corrosion cracking resistance of the Inconel 625/X80 weld overlay by post-weld heat treatment
The effect of post-weld heat treatment (PWHT) on the microstructure, penetration and distribution of hydrogen, and sulfide stress corrosion cracking (SSCC) behavior was investigated to improve the cracking res...
-
Article
Open AccessMonocytes release cystatin F dimer to associate with Aβ and aggravate amyloid pathology and cognitive deficits in Alzheimer’s disease
Understanding the molecular mechanisms of Alzheimer’s disease (AD) has important clinical implications for guiding therapy. Impaired amyloid beta (Aβ) clearance is critical in the pathogenesis of sporadic AD, ...
-
Article
Open AccessThe prognostic significance and potential mechanism of DBF4 zinc finger in hepatocellular carcinoma
DBF4 zinc finger (DBF4) is a critical component involved in DNA replication and cell proliferation. It acts as a positive regulator of the cell division cycle 7 kinase. In this study, our investigation encompa...
-
Article
Open AccessGlycometabolism and lipid metabolism related genes predict the prognosis of endometrial carcinoma and their effects on tumor cells
Glycometabolism and lipid metabolism are critical in cancer metabolic reprogramming. The primary aim of this study was to develop a prognostic model incorporating glycometabolism and lipid metabolism-related g...