3,337 Result(s)
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Article
Knocking out Selenium Binding Protein 1 Induces Depressive-Like Behavior in Mice
Selenium binding protein 1 (SELENBP1) is involved in neurologic disorders, such as multiple sclerosis, spinal cord injury, Parkinson’s disease, epilepsy, and schizophrenia. However, the role of SELENBP1 in the...
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The Effect of Blending Ratio on the Structure and Properties of the PPR/PS In situ Fiber Reinforced System Prepared by Multi-Flow Vibration Injection Molding
To enhance the mechanical properties of polypropylene random copolymer (PPR), polystyrene (PS) with four different contents were added to the PPR matrix through melt blending. Subsequently, using the Multi-Flo...
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Optimal Strategy for Aircraft Pursuit-evasion Games via Self-play Iteration
In this paper, the pursuit-evasion game with state and control constraints is solved to achieve the Nash equilibrium of both the pursuer and the evader with an iterative self-play technique. Under the conditio...
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Open AccessDeficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
Miscarriage is a frustrating complication of pregnancy that is common among women of reproductive age. Insufficient decidualization which not only impairs embryo implantation but disturbs fetomaternal immune-t...
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Open AccessEffect of the surface coating of carbonyl iron particles on the dispersion stability of magnetorheological fluid
The dispersion stability of carbonyl iron particle (CIP)-based magnetorheological fluid (MRF) is improved by CIP, which particle is etched with hydrochloric acid (HCl) to form porous structure with many hydrox...
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Article
Hierarchical modal interaction balance cross-modal hashing for unsupervised image-text retrieval
As multimedia technologies advance, untagged image-text data processing has become central in cross-modal retrieval. However, current methods often neglect three critical issues when learning hash codes: 1. In...
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A direct polymeric carbon nitride/tungsten oxide Z-scheme heterostructure for efficient photocatalytic hydrogen generation via reforming of plastics into value-added chemicals
To promote charge transfer and separation for efficient photocatalysis, a direct Z-scheme heterostructure was constructed by coupling polymeric carbon nitride (PCN) and WO3. Interestingly, the obtained PCN/WO3 Z-...
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Open AccessBorderline personality traits mediate the relationship between negative life events and nonsuicidal self-injury in a clinical sample with youth depression
Borderline personality traits play a significant role in nonsuicidal self-injury (NSSI), particularly in depressed youths. NSSI is also highly correlated with negative life events. This research aimed to explo...
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Article
FGF21 relieves calcium oxalate-induced cell injury, apoptosis, oxidative damage and ferroptosis of renal tubular epithelial cells through activating Nrf2 signaling pathway
Nephrolithiasis is a common urological disease accompanied by high morbidity worldwide. Evidences indicate that high-level CaOx crystals in the body can lead to renal tubular epithelial cell (RTEC) injury and ...
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Article
In Situ Reconfiguration of Assembling Pattern for Modular Continuum Robots
Modular continuum robots possess significant versatility across various scenarios; however, conventional assembling methods typically rely on linear connection between modules. This limitation can impede the r...
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Open AccessGenome-wide identification and analyses of ZmAPY genes reveal their roles involved in maize development and abiotic stress responses
Apyrase is a class of enzyme that catalyzes the hydrolysis of nucleoside triphosphates/diphosphates (NTP/NDP), which widely involved in regulation of plant growth and stress responses. However, apyrase family ...
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Open AccessThe bi-directional relationships between diversified leisure activity participation and cognitive function in older adults in China: separating between-person effects from within-person effects
To examine the bi-directorial association between diversified leisure activity participation and cognitive function over a 7-year period.
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Open AccessConstructing ordered and tunable extrinsic porosity in covalent organic frameworks via water-mediated soft-template strategy
As one of the most attractive methods for the synthesis of ordered hierarchically porous crystalline materials, the soft-template method has not appeared in covalent organic frameworks (COFs) due to the incomp...
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Open AccessHigh yield electrosynthesis of oxygenates from CO using a relay Cu-Ag co-catalyst system
As a sustainable alternative to fossil fuel-based manufacture of bulk oxygenates, electrochemical synthesis using CO and H2O as raw materials at ambient conditions offers immense appeal. However, the upscaling of...
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Article
MiRNA-192-5p-targeted activated leukocyte cell adhesion molecule improved inflammatory injury of neonatal necrotizing enterocolitis
Neonatal necrotizing enterocolitis (NEC) is a common gastrointestinal emergency in neonates. MiRNA-192-5p was found associated with ulcerative colitis (UC) progression, also with aberrant expression in intesti...
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Article
Open AccessGenetic variations in ACE2 gene associated with metabolic syndrome in southern China: a case–control study
Metabolic syndrome (MetS) is closely related to cardiovascular and cerebrovascular diseases, and genetic predisposition is one of the main triggers for its development. To identify the susceptibility genes for...
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Open AccessRapid development and mass production of SARS-CoV-2 neutralizing chicken egg yolk antibodies with protective efficacy in hamsters
Despite the record speed of develo** vaccines and therapeutics against the SARS-CoV-2 virus, it is not a given that such success can be secured in future pandemics. In addition, COVID-19 vaccination and appl...
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Development of novel nitric oxide production inhibitors based on the 7H-pyrrolo[2,3-d]pyrimidine scaffold
Nitric oxide (NO), the smallest signaling molecule known, can be excessively produced by overexpressed inducible nitric oxide synthase (iNOS), and eventually leads to multiple inflammatory related diseases. Th...
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Open AccessThe deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis
Rhabdomyosarcoma (RMS) is a rare malignancy and the most common soft tissue sarcoma in children. Vasculogenic mimicry (VM) is a novel tumor microcirculation model different from traditional tumor angiogenesis,...
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Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E2 in the lateral parabrachial nucleus of male rats
It has been shown that prostaglandin (PG) E2 synthesized in the lateral parabrachial nucleus (LPBN) is involved in lipopolysaccharide-induced fever. But the neural mechanisms of how intra-LPBN PGE2 induces fever ...