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Jun Chen
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Article
Clinical and functional characterization of a novel KCNJ11 (c.101G > A, p.R34H) mutation associated with maturity-onset diabetes mellitus of the young type 13
This study aimed to describe the clinical features, diagnostic and therapeutic course of a patient with MODY13 caused by KCNJ11 (c.101G > A, p.R34H) and how it contributes to the pathogenesis of MODY13, and to...
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Open AccessCorrection: Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system
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Open AccessAssociation between lipid accumulation product and psoriasis among adults: a nationally representative cross-sectional study
Lipid accumulation product (LAP) is an accessible and relatively comprehensive assessment of obesity that represents both anatomical and physiological lipid accumulation. Obesity and psoriasis are potentially ...
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Influence of environmental filtering and spatial processes on macroinvertebrate community in urban lakes in the Taihu Lake Basin, China
Studies identifying the relative importance of multiple ecological processes in macroinvertebrate communities in urban lakes at a basin scale are rare. In this study, 14 urban lakes in the Taihu Lake Basin wer...
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Open AccessThe role of peripheral white blood cell counts in the association between central adiposity and glycemic status
Although central adiposity is a well-known risk factor for diabetes, the underlying mechanism remains unclear. The aim of this study was to explore the potential mediation role of circulating WBC counts in the...
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LncRNA CCRR maintains Ca2+ homeostasis against myocardial infarction through the FTO-SERCA2a pathway
Cardiac conduction regulatory RNA (CCRR) has been documented as an antiarrhythmic lncRNA in our earlier investigation. This study aimed to evaluate the effects of CCRR on SERCA2a and the associated Ca2+ homeostas...
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Open AccessiTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge of the mechanisms and biomarkers associate...
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Open AccessEfficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study
Chimeric antigen receptor T (CAR-T) cells have been proposed for HIV-1 treatment but have not yet demonstrated desirable therapeutic efficacy. Here, we report newly developed anti-HIV-1 CAR-T cells armed with ...
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Open AccessAssociation between serum vitamin A and body mass index in adolescents from NHANES 1999 to 2006
Vitamin A plays a pivotal role in health, particularly in regulating fat metabolism. Despite its significance, research into the direct relationship between vitamin A levels and obesity, especially among adole...
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High-resolution ground motion generation with time–frequency representation
Data-driven deep learning application in earthquake engineering highlights the insufficient quantity and the imbalanced feature distribution of measured ground motions, which can be mitigated with artificial o...
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A Twisting Fabrication Process for Wearable Electronic Devices
The advancement of integrated circuits has made it easier to reduce the size of increasingly potent wearable electronic devices. However, it is still difficult to seamlessly integrate electronic systems enabli...
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Open AccessIntegrative analysis of single-cell and bulk RNA sequencing unveils a machine learning-based pan-cancer major histocompatibility complex-related signature for predicting immunotherapy efficacy
Major histocompatibility complex (MHC) could serve as a potential biomarker for tumor immunotherapy, however, it is not yet known whether MHC could distinguish potential beneficiaries. Single‐cell RNA sequenci...
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FPGA-based position reconstruction method for neutron beam flux spatial distribution measurement in BNCT
A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy (BNCT) is being developed based on the two-dimensional Micromegas detector. To address the issue of l...
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Ferroelectric/semiconductor (BiFeO3–BaTiO3/AlN) lead-free ceramic composites featuring enhanced real-time d33 temperature stability
Although the BiFeO3–BaTiO3 (BF–BT)-based lead-free ceramics possess the ultrahigh Curie temperature Tc and relatively large piezoelectric constant d33, there is still a huge fluctuation of the real-time d33 in th...
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In vivo real-time monitoring delayed administration of M2 macrophages to enhance healing of tendon by NIR-II fluorescence imaging
The administration time is a critical but long-neglected point in cell therapy based on macrophages because the incorrect time of macrophage administration could result in diverse outcomes regarding the same m...
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Permanent fluidic magnets for liquid bioelectronics
Brownian motion allows microscopically dispersed nanoparticles to be stable in ferrofluids, as well as causes magnetization relaxation and prohibits permanent magnetism. Here we decoupled the particle Brownian...
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Polypyrrole confined in network of composite hydrogel as adsorbent for enhanced adsorption of Cr(VI) in aqueous solutions
The treatment of Cr(VI) wastewater containing hexavalent chromium is a difficult problem. The World Health Organization (WHO) "Drinking Water Quality Standard" stipulates that the maximum allowable limit of ch...
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Enhancing lithium-metal battery longevity through minimized coordinating diluent
Extending the lifespan of lithium (Li) batteries involves managing reactions at the Li anode and stabilizing the solid–electrolyte interphase (SEI) through strategic regulation of the electrolyte composition. ...
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Open AccessDevelopment and validation of a smartwatch algorithm for differentiating physical activity intensity in health monitoring
To develop and validate a machine learning based algorithm to estimate physical activity (PA) intensity using the smartwatch with the capacity to record PA and determine outdoor state. Two groups of participan...
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CSCNN: Lightweight Modulation Recognition Model for Mobile Multimedia Intelligent Information Processing
A new round of global technological revolution and industrial transformation is accelerating. The era of 6G is on the horizon, envisioning the creation of an integrated network spanning across regions, airspac...
