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Article
Comparative Transcriptome Analysis of Shell-Matrix-Protein Genes and Observation of the Shell Microstructure in the Deep-Sea Clam Calyptogena marissinica
The deep-sea clam Calyptogena marissinica is widely distributed in the Haima cold seep ecosystem on the northwestern slope of the South China Sea with low pH values, low temperature and high pressure. Limited inf...
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Article
Fully automated measurement of femoral neck axis line in anatomical coordinate system using CT images
The femoral neck is the most vulnerable site for fractures within the hip joint. Due to its complex three-dimensional structure and special blood supply mechanism, the treatment of femoral neck fractures is di...
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Article
Open AccessCorrelative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment
In the nucleus, biological processes are driven by proteins that diffuse through and bind to a meshwork of nucleic acid polymers. To better understand this interplay, we present an imaging platform to simultan...
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Article
Correction for: Cornel iridoid glycoside exerts a neuroprotective effect on neuroinflammation in rats with brain injury by inhibiting NF-kB and STAT3
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Article
Open AccessA Beginner’s Guide to Artificial Intelligence for Ophthalmologists
The integration of artificial intelligence (AI) in ophthalmology has promoted the development of the discipline, offering opportunities for enhancing diagnostic accuracy, patient care, and treatment outcomes. ...
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Article
Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients
Background: Acute myeloid leukemia (AML) patients with various nucleophosmin 1 (NPM1) mutations are controversial in the prognosis. This study aimed to investigate the prognosis of patients according to types of
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Article
Open AccessPredicting equilibrium distributions for molecular systems with deep learning
Advances in deep learning have greatly improved structure prediction of molecules. However, many macroscopic observations that are important for real-world applications are not functions of a single molecular ...
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Article
Open AccessThe burden and predictors of 30-day unplanned readmission in patients with acute liver failure: a national representative database study
Liver diseases were significant source of early readmission burden. This study aimed to evaluate the 30-day unplanned readmission rates, causes of readmissions, readmission costs, and predictors of readmission...
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Article
Loeys-Dietz syndrome with concomitant aplastic anemia
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Article
Bakuchiol regulates TLR4/MyD88/NF-κB and Keap1/Nrf2/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo
Bakuchiol (Bak) possesses a protective effect in acute lung injury (ALI). Nonetheless, the molecular processes that regulate the protective activity of Bak in ALI remain elusive. Lipopolysaccharide (LPS)–treat...
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Article
Tough Semi-interpenetrating Polyvinylpyrrolidone/Polyacrylamide Hydrogels Enabled by Bioinspired Hydrogen-bonding Induced Phase Separation
Semi-interpenetrating (semi-IPN) hydrogels formed by the continuous interpenetration of cross-linked polymer network and linear non-crosslinked polymer with multifunctionality are widely used in biomedical and...
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Article
Advancements in investigating the role of cerebral small vein loss in Alzheimer’s disease–related pathological changes
Alzheimer’s disease (AD) is the prevailing type of dementia in the elderly, yet a comprehensive comprehension of its precise underlying mechanisms remains elusive. The investigation of the involvement of cereb...
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Article
Open AccessDiphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects
Diphthamide is a modified histidine residue unique for eukaryotic translation elongation factor 2 (eEF2), a key ribosomal protein. Loss of this evolutionarily conserved modification causes developmental defect...
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Article
Effect of intestinal permeability and phagocytes diffusion rate on pattern structure of Crohn’s disease based on the Turing–Hopf bifurcation
The patchy inflammatory pattern in the gastrointestinal tract is one of the typical features of Crohn’s disease, and revealing the evolutionary mechanism of Crohn’s disease is helpful to further understand its...
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Article
Open AccessHigh frequency deep brain stimulation of the dorsal raphe nucleus prevents methamphetamine priming-induced reinstatement of drug seeking in rats
Drug addiction represents a multifaceted and recurrent brain disorder that possesses the capability to create persistent and ineradicable pathological memory. Deep brain stimulation (DBS) has shown a therapeut...
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Article
Open AccessEffects of combination of strength and balance training on postural control and functionality in people with chronic ankle instability: a systematic review and meta analysis
To identify the effects of strength and balance training on dynamic balance and patient reported outcomes in people with chronic ankle instability(CAI).
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Article
An adaptive welding method for grooves with position and size errors
A large batch of mass-produced components, represented by architectural steel structure joint spheres, is influenced by the upstream processing technology level, making it difficult to maintain the position an...
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Article
Facile access to a methylthiocoumarinyl formate as highly selective and sensitive fluorescent probe for hypochlorite
Development of effective methods for analyzing hypochlorite is of great significance due to the crucial role of hypochlorite in live organisms, as an endogenously produced reactive oxygen species (ROS) in the ...
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Article
Recent progress in all-inorganic tin-based perovskite solar cells: a review
Recently, power conversion efficiency (PCE) of organic–inorganic hybrid perovskite solar cells (PSCs) has been improved to 26.1%. However, the toxicity issue of lead still hinders the large-scale commercial pr...
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Article
Open AccessKnowledge, attitude, and practice toward weight management among diabetic patients in Qidong City, Jiangsu Province
Weight management is an effective prevention and treatment strategy for diabetes mellitus. This study aimed to assess the knowledge, attitude, and practice (KAP) of diabetic patients towards weight management.
