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Article
Rutin alleviates Sjogren’s syndrome via CaR/NLRP3/NF-κB signal pathway
Sjogren’s syndrome (SS) is an autoimmune disease. Its mechanism and treatment methods are unclear. The purpose of this study was to investigate the effects of rutin (Ru) on SS. Proteomics was used to detect di...
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Article
An Exploration of How Students Prioritize Help-Seeking Sources in Online Learning Environments
The aim of this study is to analyze how undergraduate learners seek academic help online at a public university in the United States with Q methodology. Upon completion of the study, we identified three groups...
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Article
Clinical significance of the expression levels of serum transforming growth factor-β and CXC type chemokine ligand 13 in primary Sjogren’s syndrome patients
The aim of this study was to investigate the expression levels of the serum transforming growth factor-β1 (TGF-β1) CXC type chemokine ligand 13 (CXCL13) in primary Sjogren’s syndrome (pSS) patients and its cor...
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Article
Open AccessRecent development of surface-enhanced Raman scattering for biosensing
Surface-Enhanced Raman Scattering (SERS) technology, as a powerful tool to identify molecular species by collecting molecular spectral signals at the single-molecule level, has achieved substantial progresses ...
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Article
Open AccessOryzalexin S biosynthesis: a cross-stitched disappearing pathway
Rice produces many diterpenoid phytoalexins and, reflecting the importance of these natural products in this important cereal crop plant, its genome contains three biosynthetic gene clusters (BGCs) for such metab...
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Article
Pre-Service Teachers’ Instructional Design Decision-Making for Technology Integration
Instructional design problems are one of the most complicated and ill-structured types of problems due to the dynamic nature of design problems and decision-making processes. Formulating instructional design s...
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Article
A Design-Based Research Study Exploring Pre-service Teachers’ Instructional Design Decision-Making for Technology Integration
Teachers’ decisions for instructional design and technology integration influence their teaching practices and student learning performances. Technology-integrated learning environments have been widely levera...
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Article
Fostering pedagogical reasoning and dynamic decision-making practices: a conceptual framework to support learning design in a digital age
Digital learning environments are dynamic systems that require learning designers to leverage environmental conditions and the needs of their learners. While many frameworks and studies have explored pedagogic...
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Article
Embracing Children’s Voice to Support Teachers’ Pedagogical Reasoning and Decision-Making for Technology Enhanced Practices in Early Childhood Classrooms
While several studies have been conducted exploring teachers’ pedagogical reasoning practices, few studies have explored the influence of learning audiences’ impact on teacher’s decisions related to technology...
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Article
Tunable upconversion luminescence and enhanced temperature sensitive properties from Bi2Ti2O7:Yb3+/Er3+ nanofibers
Unraveling the morphology of the sensing material is of paramount in realizing the better sensitivity. For this purpose, the Bi2Ti2O7:Yb3+/Er3+ nanofibers (0:1, 4:1, 8:1, 15:1, 20:1) and nanoparticles were synthe...
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Article
An Examination of the Systemic Reach of Instructional Design Models: a Systematic Review
The majority of instructional design models have directed focus on instructional design activities such as analysis, design, development, implementation, and evaluation. Criticisms regarding instructional desi...
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Article
Author Correction: CYP72A enzymes catalyse 13-hydrolyzation of gibberellins
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
CYP72A enzymes catalyse 13-hydrolyzation of gibberellins
Bioactive gibberellins (GAs or diterpenes) are essential hormones in land plants that control many aspects of plant growth and development. In flowering plants, 13-OH GAs (having low bioactivity—for example, GA1)...
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Article
Open AccessSpatio-temporal analysis of the relationship between meteorological factors and hand-foot-mouth disease in Bei**g, China
Hand-foot-mouth disease (HFMD) is a common infectious disease in China and occurs mostly in infants and children. Bei**g is a densely populated megacity, in which HFMD has been increasing in the last decade. ...
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Article
Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain
The absolute quantitation of lipids at the lipidome-wide scale is a challenge but plays an important role in the comprehensive study of lipid metabolism.
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Chapter and Conference Paper
Terminal Sliding Mode Control of a Boost Converter
In this paper, a terminal sliding mode (TSM) control method for the boost converter is studied. First of all, the nonlinear model of boost converter is established. Then a change of coordinate is employed such...
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Article
Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis
The oxygenation reactions catalyzed by cytochromes P450 (CYPs) play critical roles in plant natural products biosynthesis. At the same time, CYPs are one of most challenging enzymes to functionally characteriz...
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Article
Open AccessSpatiotemporal analysis of particulate air pollution and ischemic heart disease mortality in Bei**g, China
Few studies have used spatially resolved ambient particulate matter with an aerodynamic diameter of <10 μm (PM10) to examine the impact of PM10 on ischemic heart disease (IHD) mortality in China. The aim of our s...
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Article
Open AccessIncreasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering
Engineering biosynthetic pathways in heterologous microbial host organisms offers an elegant approach to pathway elucidation via the incorporation of putative biosynthetic enzymes and characterization of resul...
