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Article
Expression and clinical significance of hypoxia-induced long non-coding RNA TCONS_I2_00001955 in breast cancer
Long non-coding RNAs (lncRNAs) have been found to play important roles in occurrence, development, and metastasis of various tumors. We aimed to screen long non-coding RNAs (lncRNAs) that promote invasion and ...
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Article
In vitro drug screening models derived from different PC12 cell lines for exploring Parkinson’s disease based on electrochemical signals of catecholamine neurotransmitters
Gold nanostructures and a Nafion modified screen-printed carbon electrode (Nafion/AuNS/SPCE) were developed to assess the cell viability of Parkinson’s disease (PD) cell models. The electrochemical measuremen...
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Article
Insight into deformation allocation in the multi-pass roll forming of a double-walled brazed tube
Deformation allocation is an important factor that affects 720° curling forming from copper-coated steel strips to double-walled brazed tubes (DWBTs). In this study, four schemes of deformation allocation, con...
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Article
Failure Envelopes of Single-Plate Rigid Helical Anchors for Floating Offshore Wind Turbine
Helical anchor is a kind of novel foundation for floating offshore wind turbines, which should be subjected to combined tensile loading caused by wind, wave and current. However, the research about the capacit...
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Article
Open AccessMelatonin inhibits senescence-associated melanin pigmentation through the p53-TYR pathway in human primary melanocytes and the skin of C57BL/6 J mice after UVB irradiation
UVB exposure accelerates skin aging and pigmentation. Melatonin effectively regulates tyrosinase (TYR) activity and aging. The purpose of this study was to determine the association between premature senescenc...
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Article
Open AccessSingle-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis
To investigate the effect of pentoxifylline (PTX) on Chlorine (Cl2)-induced acute lung injury (ALI) by single-cell RNA sequencing (scRNA-seq). Female BALB/c mice were exposed to Cl2 at 400 ppm for 15 min. H&E sta...
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Article
Open AccessProtective effects of pentoxifylline against chlorine-induced acute lung injury in rats
Chlorine is a chemical threat agent that can be harmful to humans. Inhalation of high levels of chlorine can lead to acute lung injury (ALI). Currently, there is no satisfactory treatment, and effective antido...
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Article
The study of schizogenous formation of secretory ducts in Ferula ferulaeoides (Steud.) Korov.
The secretory ducts of Ferula ferulaeoides (Steud.) Korov. are the main tissue of synthesis, secretion, and accumulation of resin. The formation of secretory ducts is closely related to the harvest and quality of...
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Article
Open AccessImpact of cumulative cisplatin dose in childhood nasopharyngeal carcinoma based on neoadjuvant chemotherapy response in the intensity-modulated radiotherapy era: a real-world study
We aimed to comprehensively investigate the optimal cumulative cisplatin dose during concurrent chemoradiotherapy (CC-CCD) for locoregionally advanced nasopharyngeal carcinoma (CA-LANPC) with different tumor r...
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Article
Determination of continuous constitutive relationship of weld zone of high-strength steel rectangular welded tube
For QSTE700 high-strength steel rectangular welded tube, the mechanical properties of the weld zone vary with the distance from the centerline of the weld. Therefore, the accurate description of constitutive r...
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Article
A high-performance amperometric sensor based on a monodisperse Pt–Au bimetallic nanoporous electrode for determination of hydrogen peroxide released from living cells
A neotype electrochemical sensor based on a three-dimensional nanoporous gold (3D-NPG) electrode decorated with ultra-thin platinum nanoparticles (Pt NPs) was fabricated for high-performance electrocatalysis a...
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Article
Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China
Rodent populations are known to be reservoirs of viruses with the potential to infect humans. However, a large number of such viruses remain undiscovered. In this study, we investigated the shedding of unknown...
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Chapter and Conference Paper
The Principle and Design of Separate Fingerprint Identification System
Separate fingerprint identification system (SFIS) is composed of high-speed DSP (digital signal processor), SRAM and Flash chip, whose modules include fingerprint entry, image processing, fingerprint contrasti...
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Article
Daytime nap** and risk of type 2 diabetes: a meta-analysis of prospective studies
Prospective studies reported inconsistent findings on the relationship between daytime nap** and risk of type 2 diabetes (T2D). Categorized and dose-response meta-analyses were performed to quantify this rel...
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Article
Roles of A20 in autoimmune diseases
A20 (TNFAIP3), known to inhibit NF-κB function by deubiquitinating-specific NF-κB signaling molecules, has been found in many cell types of the immune system. Recent findings suggest that A20 is essential for ...
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Article
Experimental and theoretical prediction of the redox potentials of noradrenaline and its supramolecular complex with glycine
The redox reaction of N-protonated noradrenalin (NA) is a two-proton-two-electron reaction in aqueous solution. NA can be oxidated to N-protonated noradrenalin quinone (NAquinone). The standard electrode poten...
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Article
Open AccessTranscriptome analysis of genes involved in defence response in Polyporus umbellatus with Armillaria mellea infection
Polyporus umbellatus, a species symbiotic with Armillaria mellea and it also exhibits substantial defence response to Armillaria mellea infection. There are no genomics resources databases for understanding the m...
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Article
The Roles of Egr-2 in Autoimmune Diseases
Being a member of the early growth response (Egr) family of transcription factors, Egr-2 is expressed in a variety of cell types of the immune system. Recent findings imply that Egr-2 is important in the devel...
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Article
Generation by reverse genetics of an effective attenuated Newcastle disease virus vaccine based on a prevalent highly virulent Chinese strain
To investigate whether the differences between the circulating Newcastle disease virus (NDV) isolates and the used vaccine might account for the current ND outbreaks in vaccinated poultry flocks.
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Article
Open AccessOxalic acid and sclerotial differentiation of Polyporus umbellatus
The present investigation aimed to uncover the effects of exogenous oxalic acid during the sclerotial formation of Polyporus umbellatus, with an emphasis on determining the content of the endogenic oxalic acid in...