1,048 Result(s)
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Wei He
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Article
Open AccessElevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis
Clear cell renal cell carcinoma (ccRCC), the most common pathological subtype of kidney cancer, accounts for approximately 70% to 80% of all cases. Histone deacetylase 10 (HDAC10) belongs to the HDAC class IIb...
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Open AccessDisruption of maternal vascular remodeling by a fetal endoretrovirus-derived gene in preeclampsia
Preeclampsia, one of the most lethal pregnancy-related diseases, is associated with the disruption of uterine spiral artery remodeling during placentation. However, the early molecular events leading to preecl...
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Double-edged sword effect of informal status on work procrastination: the roles of career calling and workload
Informal status has strong positive implications in the field of organizational behavior, but it also has some harmful effects on individuals. Based on conservation of resources (COR) theory, this study constr...
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The earliest evidence for a microblade adaptation in the remote, high altitude regions of the Tibetan Plateau
Microblade assemblages are among the most common prehistoric archaeological materials found on the Tibetan Plateau (TP) and are thought to indicate large scale migration to and settlement of the TP. Few microb...
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An online intrusion detection method for industrial control systems based on extended belief rule base
Intrusion detection in industrial control systems (ICS) is crucial for maintaining the security of physical information systems. However, the existing models predominantly rely on black-box approaches, which e...
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Open AccessComprehensive analysis of m6A modification in immune infiltration, metabolism and drug resistance in hepatocellular carcinoma
N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However, there is still limited understanding of the comprehensive e...
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Properties of some elliptic Hill’s potentials
We study Hill’s differential equation with potential expressed by elliptic functions which arises in some problems of physics and mathematics. Analytical method can be applied to study the local properties of ...
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Open AccessManipulating the diffusion energy barrier at the lithium metal electrolyte interface for dendrite-free long-life batteries
Constructing an artificial solid electrolyte interphase (SEI) on lithium metal electrodes is a promising approach to address the rampant growth of dangerous lithium morphologies (dendritic and dead Li0) and low C...
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Open AccessDietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs
Cold stress has negative effects on the growth and health of mammals, and has become a factor restricting livestock development at high latitudes and on plateaus. The gut-liver axis is central to energy metabo...
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Open AccessUnsupervised deep representation learning enables phenotype discovery for genetic association studies of brain imaging
Understanding the genetic architecture of brain structure is challenging, partly due to difficulties in designing robust, non-biased descriptors of brain morphology. Until recently, brain measures for genome-w...
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Open AccessPianno: a probabilistic framework automating semantic annotation for spatial transcriptomics
Spatial transcriptomics has revolutionized the study of gene expression within tissues, while preserving spatial context. However, annotating spatial spots’ biological identity remains a challenge. To tackle t...
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Open AccessFlexible batch electrodialysis for low-cost solar-powered brackish water desalination
Globally, 1.6 billion people in rural regions face water scarcity. Expanding freshwater access via brackish groundwater desalination can provide additional resources to address this challenge. In this study, w...
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Correction: Microstructure evolution and growth kinetics of intermetallic compound in SAC305/Ag and SAC305/Cu solder joints during solid-state aging
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Open AccessControl of breathing by orexinergic signaling in the nucleus tractus solitarii
Orexin signaling plays a facilitatory role in respiration. Abnormalities in orexin levels correlate with disordered breathing patterns and impaired central respiratory chemoreception. Nucleus tractus solitarii...
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Preliminary establishment and validation of the inversion method for growth and remodeling parameters of patient-specific abdominal aortic aneurysm
Traditional medical imaging and biomechanical studies have challenges in analyzing the long-term evolution process of abdominal aortic aneurysm (AAA). The homogenized constrained mixture theory (HCMT) allows f...
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Open AccessQuantifying the interfacial triboelectricity in inorganic-organic composite mechanoluminescent materials
Mechanoluminescence (ML) sensing technologies open up new opportunities for intelligent sensors, self-powered displays and wearable devices. However, the emission efficiency of ML materials reported so far sti...
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Significance of the total renal chronicity score in predicting renal outcome in PLA2R-associated membranous nephropathy
Phospholipase A2 receptor (PLA2R)-associated membranous nephropathy accounts for the majority of membranous nephropathy; however, few studies have determined the prognostic impact and clinical application of r...
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Open AccessCDK12 is a potential biomarker for diagnosis, prognosis and immunomodulation in pan-cancer
Cell cycle-dependent protein kinase 12 (CDK12) plays a key role in a variety of carcinogenesis processes and represents a promising therapeutic target for cancer treatment. However, to date, there have been no...
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Open Accessm6A methylation modification and immune infiltration analysis in osteonecrosis of the femoral head
Osteonecrosis of the femoral head (ONFH) is a elaborate hip disease characterized by collapse of femoral head and osteoarthritis. RNA N6-methyladenosine (m6A) plays a crucial role in a lot of biological proces...
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Metabolomics-based study of chemical compositions in cellulase additives derived from a tobacco-origin Bacillus subtilis and their impact on tobacco sensory attributes
To enhance the quality of tobacco leaves and optimize the smoking experience, diverse strains of functional bacteria and their associated metabolites have been used in tobacco aging. Exogenous cellulase additi...
