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Article
Open AccessCLK2 mediates IκBα-independent early termination of NF-κB activation by inducing cytoplasmic redistribution and degradation
Activation of the NF-κB pathway is strictly regulated to prevent excessive inflammatory and immune responses. In a well-known negative feedback model, IκBα-dependent NF-κB termination is a delayed response pat...
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Article
Single transition-metal atoms anchored on a novel Dirac-dispersive π-π conjugated holey graphitic carbon nitride substrate: computational screening toward efficient bifunctional OER/ORR electrocatalysts
Nonprecious-metal-group single-metal-atom catalysts with bifunctional catalytic capabilities toward the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) are highly sought after in energy-con...
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Article
Therapeutic application of circular RNA aptamers in a mouse model of psoriasis
Efforts to advance RNA aptamers as a new therapeutic modality have been limited by their susceptibility to degradation and immunogenicity. In a previous study, we demonstrated synthesized short double-stranded...
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Article
High dimensional proteomic map** of bone marrow immune characteristics in immune thrombocytopenia
To investigate the role of co-stimulatory and co-inhibitory molecules on immune tolerance in immune thrombocytopenia (ITP), this study mapped the immune cell heterogeneity in the bone marrow of ITP at the sing...
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Article
Boosting ammonia production in electrocatalytic NOx reduction on a robust Fe/FeMoO4 catalyst
Electrocatalytic reduction of nitrate \(({\rm{N}}{{\rm{O}}_3}^ - )\) ( NO ...
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Article
Open AccessKinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis
Kinesin family member 3A (KIF3A) is a microtubule-oriented motor protein that belongs to the kinesin-2 family for regulating intracellular transport and microtubule movement. In this study, we characterized th...
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Article
Bioinspired design of integral molded Janus silk fibroin-MXene evaporator for efficient solar vapor generation
Solar vapor generation is a promising sustainable technology that uses solar distillation to produce fresh water from seawater and wastewater, hel** relieve global water resource shortage. Here, inspired by ...
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Article
Nucleic acid and protein methylation modification in renal diseases
Although great efforts have been made to elucidate the pathological mechanisms of renal diseases and potential prevention and treatment targets that would allow us to retard kidney disease progression, we stil...
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Article
Modulated noble metal/2D MOF heterostructures for improved hydrogen storage of MgH2
The conjugation of external species with two-dimensional (2D) materials has broad application prospects. In this study, we have explored the potential of noble metal/2D MOF heterostructures in hydrogen storage...
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Article
Regulating ion transport behaviors toward dendrite-free potassium metal batteries: recent advances and perspectives
With abundant potassium resources and high capacity, potassium metal batteries (PMBs) present a compelling option for the next generation of energy storage technology. However, PMBs suffer from an unstable ano...
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Article
Open AccessRetraction Note: Digital transformation, green innovation, and carbon emission reduction performance of energy-intensive enterprises
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Article
Open AccessIncreased di-(2-ethylhexyl) phthalate exposure poses a differential risk for adult asthma clusters
DEHP, a common plasticizer known for its hormone-disrupting properties, has been associated with asthma. However, a significant proportion of adult asthma cases are “non-atopic”, lacking a clear etiology.
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Article
Open AccessRETRACTED ARTICLE: Digital transformation, green innovation, and carbon emission reduction performance of energy-intensive enterprises
Digital transformation and green innovation are powerful initiatives to achieve carbon peaking, carbon neutrality targets and high-quality economic development. Using a sample of high energy-consuming listed e...
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Article
Open AccessMonitoring trends in the absolute lymphocyte count and the neutrophil-to-lymphocyte ratio in patients with breast cancer receiving eribulin
Studies have shown that the absolute lymphocyte count (ALC) and the neutrophil-to-lymphocyte ratio (NLR) are related to the outcomes in patients with breast cancer receiving specific chemotherapies. However, t...
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Article
Observation of plaid-like spin splitting in a noncoplanar antiferromagnet
Spatial, momentum and energy separation of electronic spins in condensed-matter systems guides the development of new devices in which spin-polarized current is generated and manipulated1–3. Recent attention on a...
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Article
Preparation of vanadium-based electrode materials and their research progress in solid-state flexible supercapacitors
Solid-state flexible supercapacitors (SCs) have many advantages of high specific capacitance, excellent flexibility, fast charging and discharging, high power density, environmental friendliness, high safety, ...
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Article
Hesperetin derivative 2a inhibits lipopolysaccharide-induced acute liver injury in mice via downregulation of circDcbld2
Acute liver injury (ALI) is a complex, life-threatening inflammatory liver disease, and persistent liver damage leads to rapid decline and even failure of liver function. However, the pathogenesis of ALI is st...
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Article
Open AccessSelective autophagy in cancer: mechanisms, therapeutic implications, and future perspectives
Eukaryotic cells engage in autophagy, an internal process of self-degradation through lysosomes. Autophagy can be classified as selective or non-selective depending on the way it chooses to degrade substrates....
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Article
A Novel Multi-Functional Fluorescence Probe for the Detection of Al3+/Zn2+/Cd2+ and its Practical Applications
A novel multi-functional fluorescence probe HMIC based on hydrazide Schiff base has been successfully synthesized and characterized. It can distinguish Al3+/Zn2+/Cd2+ in ethanol, in which fluorescence emission wi...
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Article
Association between alcohol consumption and sleep traits: observational and mendelian randomization studies in the UK biobank
Previous studies have shown that excessive alcohol consumption is associated with poor sleep. However, the health risks of light-to-moderate alcohol consumption in relation to sleep traits (e.g., insomnia, sno...
