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Article
Overexpression of circZNF720 Inhibits Hepatocellular Carcinoma Progression by Regulating miR-421/MAPK9
Hepatocellular carcinoma (HCC) is characterized by high incidence, high death rate and poor long term prognosis. Abnormal expression of circular RNA (circRNA) has been demonstrated to be closely associated wit...
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Article
HIV encephalopathy is contributed by macrophages and microglia
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Article
Open AccessGenome-wide identification and analysis of Oleosin gene family in four cotton species and its involvement in oil accumulation and germination
Cotton is not only a major textile fiber crop but also a vital oilseed, industrial, and forage crop. Oleosins are the structural proteins of oil bodies, influencing their size and the oil content in seeds. In ...
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Article
Open AccessPRCC reduces the sensitivity of cancer cells to DNA damage by inhibiting JNK and ATM/ATR pathways and results in a poor prognosis in hepatocellular carcinoma
The proline rich mitotic checkpoint control factor (PRCC) is involved in the splicing process of pre-mRNA. This study aims to elucidate PRCC molecular function, regulatory mechanism and diagnostic value in hep...
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Article
Open AccessMetabolomics analysis reveals Embden Meyerhof Parnas pathway activation and flavonoids accumulation during dormancy transition in tree peony
Bud dormancy is a sophisticated strategy which plants evolve to survive in tough environments. Endodormancy is a key obstacle for anti-season culture of tree peony, and sufficient chilling exposure is an effec...
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Article
Open AccessRetraction Note: LncRNA TUG1 was upregulated in osteoporosis and regulates the proliferation and apoptosis of osteoclasts
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13018-020-02000-1.
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Open AccessRETRACTED ARTICLE: LncRNA TUG1 was upregulated in osteoporosis and regulates the proliferation and apoptosis of osteoclasts
Long non-coding RNA (LncRNA) TUG1 plays critical roles in the development of human cancers. Its inhibition has been proved to participate in ankylosing spondylitis, which is an inverse pathological procedure o...
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Article
Open AccessRNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
N6-methyladenosine (m6A) is an important epitranscriptomic mark with high abundance in the brain. Recently, it has been found to be involved in the regulation of memory formation and mammalian cortical neurogenes...
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Article
Distributions and Relationships of CO2, O2, and Dimethylsulfide in the Changjiang (Yangtze) Estuary and Its Adjacent Waters in Summer
The distributions and relationships of O2, CO2, and dimethylsulfide (DMS) in the Changjiang (Yangtze) Estuary and its adjacent waters were investigated in June 2014. In surface water, mean O2 saturation level, pa...
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Article
Open AccessIdentification and characterization of microRNAs in tree peony during chilling induced dormancy release by high-throughput sequencing
Tree peony, one of the most valuable horticultural and medicinal plants in the world, has to go through winter to break dormancy. Growing studies from molecular aspects on dormancy release process have been re...
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Article
Hyaluronic acid binding protein 1 overexpression is an indicator for disease-free survival in cervical cancer
Hyaluronic acid binding protein 1 (HABP1) is reported to overexpress in various cancer tissues and may therefore contribute to oncogenesis. However, the status of HABP1 expression in cervical cancer (CC) remai...
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Article
Open AccessCostunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cance...
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Article
Isolation and Characterization of a SOC1-Like Gene from Tree Peony (Paeonia suffruticosa)
Tree peony (Paeonia suffruticosa) is one of the well-known ornamental plants, and flowering is a major industry in its production areas, but its dormancy is a major obstacle during winter. Analysis of the molecul...
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Article
Open AccessGut–neuron interaction via Hh signaling regulates intestinal progenitor cell differentiation in Drosophila
Intestinal homeostasis is maintained by intestinal stem cells (ISCs) and their progenies. A complex autonomic nervous system spreads over posterior intestine. However, whether and how neurons regulate posterio...
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Article
Mixing, tensile and pasting properties of wheat flour mixed with raw and enzyme treated rice bran
Rice bran is a potential fiber and minerals source for nutrients enhancement of cereals food. For evaluation of rice bran applied in bread making, mixing properties, tensile and pasting properties of wheat flo...
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Article
Cloning and expression analysis of the R2R3-PsMYB1 gene associated with bud dormancy during chilling treatment in the tree peony (Paeonia suffruticosa)
Transcription factor (TF) MYB-like proteins are involved in many physiological and biochemical processes. This study isolated the full length cDNA encoding a MYB from the tree peony (Paeonia suffruticosa Andr.), ...
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Article
Preparation of przewalskinic acid A from salvianolic acid B using a crude enzyme from an Aspergillus oryzae strain
Przewalskinic acid A is a rare, water-soluble, and highly biologically active ingredient found, thus far, only in the Salvia przewalskii Maxim herb; however, the content in S. przewalskii herb is very low. In ord...
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Article
Ligand-mediated endocytosis of nanoparticles in neural stem cells: implications for cellular magnetic resonance imaging
Neural stem cells (NSCs) have great prospects in therapy for neurological disorders. However, the correlation between improved function and stem cell transplantation has not been fully elucidated. A non-invasi...
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Article
Protodioscin-glycosidase-1 hydrolyzing 26-O-β-d-glucoside and 3-O-(1 → 4)-α-l-rhamnoside of steroidal saponins from Aspergillus oryzae
A novel protodioscin-(steroidal saponin)-glycoside hydrolase, named protodioscin-glycosidase-1 (PGase-1), was purified and characterized from the Aspergillus oryzae strain. The molecular mass of this enzyme was d...
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Article
Impact of preoperative serum interleukin-2 receptor alpha levels on survival and its correlation with clinicopathological parameters in colorectal cancer
