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Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-finding trial
Colloid and/or co-load may be more effective than crystalloid for preventing postspinal anesthesia hypotension. We tested five different prophylactic norepinephrine dosages combined with colloid co-load infusi...
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Article
Firing activities of hippocampal CA1 neuron model under electromagnetic stimulation
Electromagnetic neuromodulation has exhibited obvious advantages in exploring the brain cognitive functions and the rehabilitation of brain diseases. The hippocampus is involved in various cognitive processes ...
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Article
Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission
Hepatocellular carcinoma (HCC) is highly metastatic and invasive. CircRNA participates in gene regulation of multiple tumor metastases, but little is known whether it is a bystander or an actual player in HCC ...
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Article
Study of dynamic welding pool for AZ31B magnesium alloy with adjustable ring mode laser welding
Adjustable ring mode laser beam welding (ARMLBW) has become a promising welding method due to its stable weld quality. In this study, the equation for the distribution of heat flux density of the ring beam was...
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Article
Assessment of HER2 status in extramammary Paget disease and its implication for disitamab vedotin, a novel humanized anti-HER2 antibody-drug conjugate therapy
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Article
Comparative Experimental Study on Heat Transfer Characteristics of Building Exterior Surface at High and Low Altitudes
The external surface heat transfer coefficient of building envelope is one of the important parameters necessary for building energy saving design, but the basic data in high-altitude area are scarce. Therefor...
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Erratum to: Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy in NSCLC
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Article
Open AccessA Compact Aerial Manipulator: Design and Control for Dexterous Operations
The lack of aerial physical interaction capability is one of the choke points limiting the extension of aerial robot applications, such as rescue missions and aerial maintenance. We present a new aerial roboti...
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Article
Open AccessEffects of the stress hyperglycemia ratio on long-term mortality in patients with triple-vessel disease and acute coronary syndrome
Risk assessment for triple-vessel disease (TVD) remain challenging. Stress hyperglycemia represents the regulation of glucose metabolism in response to stress, and stress hyperglycemia ratio (SHR) is recently ...
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Article
FPGA-based small-world spiking neural network with anti-interference ability under external noise
Neuromorphic hardware has become hotspot in the field of brain-like computing due to its advantages. However, the presence of external noise imposes challenges with respect to maintaining normal function of ne...
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Article
Open AccessToxicity of cannabidiol and its metabolites in TM3 mouse Leydig cells: a comparison with primary human Leydig cells
Cannabidiol (CBD), one of the major components extracted from the plant Cannabis sativa L., has been used as a prescription drug to treat seizures in many countries. CBD-induced male reproductive toxicity has bee...
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Article
Construction of a Hair Implantation Needle Using Injection Needles and Assessment of its Efficiency Compared with Other Planting Methods
Hair transplantation surgery requires the efficient completion of hair follicles and thus appropriate hair implantation needles. The objectives of this study were to evaluate the effectiveness and feasibility ...
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Article
An inferior vena cava-priority approach in laparoscopic isolated hepatic caudate lobectomy
Laparoscopic isolated caudate lobectomy is still a challenging operation for surgeons. The access route of the operation plays a vital role during laparoscopic caudate lobectomy. There are few references regar...
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Open AccessGovernment responses to the COVID-19 pandemic of the Gulf Cooperation Council countries: good practices and lessons for future preparedness
The COVID-19 pandemic has dramatically threatened the Gulf Cooperation Council (GCC) countries which have a large proportion of foreign workers. The governments of GCC countries have proactively implemented a ...
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Article
Open AccessPRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer
CDK4/6 inhibitors (CDK4/6i) have improved survival of patients with estrogen receptor-positive (ER+) breast cancer. However, patients treated with CDK4/6i eventually develop drug resistance and progress. RB1 loss...
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Article
Open AccessThe HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair
While hypoxic signaling has been shown to play a role in many cellular processes, its role in metabolism-linked extracellular matrix (ECM) organization and downstream processes of cell fate after musculoskelet...
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Open AccessClinical electromagnetic brain scanner
Stroke is a leading cause of death and disability worldwide, and early diagnosis and prompt medical intervention are thus crucial. Frequent monitoring of stroke patients is also essential to assess treatment e...
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Article
Using machine learning to improve Q-matrix validation
The Q-matrix, which specifies the relationship between items and attributes, is a crucial component of cognitive diagnostic models (CDMs). A precisely specified Q-matrix allows for valid cognitive diagnostic a...
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Article
New process for treating boron-bearing iron ore by flash reduction coupled with magnetic separation
Boron is an important industrial raw material often sourced from minerals containing different compounds that cocrystallize, which makes it difficult to separate the mineral phases through conventional benefic...
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Article
Nonprofit behavior altered by monetary donations: evidence from the U.S. hospice industry
This study investigates whether reliance on monetary donations alters nonprofit firms’ behaviors. Specifically, in the hospice industry, a shorter patients’ length of stay (LOS) speeds up overall patient turno...
