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  1. Article

    Open Access

    A Semi-Supervised Learning Framework for Classifying Colorectal Neoplasia Based on the NICE Classification

    Labelling medical images is an arduous and costly task that necessitates clinical expertise and large numbers of qualified images. Insufficient samples can lead to underfitting during training and poor perform...

    Yu Wang, Haoxiang Ni, Jielu Zhou, Lihe Liu in Journal of Imaging Informatics in Medicine (2024)

  2. Article

    Open Access

    Association of the fat mass index with hepatic steatosis and fibrosis: evidence from NHANES 2017–2018

    Limited population-based studies discuss the association between fat mass index (FMI) and the risk of liver diseases. This investigation utilized data from the National Health and Nutrition Examination Survey ...

    Lihe Liu, Jiaxi Lin, Minyue Yin, Lu Liu, **gwen Gao, **aolin Liu in Scientific Reports (2024)

  3. Article

    Open Access

    Maternal diet induces persistent DNA methylation changes in the muscle of beef calves

    Maternal nutrition during pregnancy can induce epigenetic alterations in the fetal genome, such as changes in DNA methylation. It remains unclear whether these epigenetic alterations due to changes in maternal...

    Rocío Amorín, Lihe Liu, Philipe Moriel, Nicolás DiLorenzo in Scientific Reports (2023)

  4. Article

    Correction to: Application of Metabolomics to the Discovery of Biomarkers for Ischemic Stroke in the Murine Model: a Comparison with the Clinical Results

    ****g Jia, Hangyao Zhang, **aoyi Liang, Yuning Dai, Lihe Liu in Molecular Neurobiology (2022)

  5. No Access

    Article

    Application of Metabolomics to the Discovery of Biomarkers for Ischemic Stroke in the Murine Model: a Comparison with the Clinical Results

    Ischemic stroke (IS) is a major cause of mortality and disability worldwide. However, the pathogenesis of IS remains unknown, and methods for early prediction and diagnosis of IS are lacking. Metabolomics can ...

    ****g Jia, Hangyao Zhang, **aoyi Liang, Yuning Dai, Lihe Liu in Molecular Neurobiology (2021)

  6. Article

    Open Access

    Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

    The evaluation of alternative splicing, including differential isoform expression and differential exon usage, can provide some insights on the transcriptional changes that occur in response to environmental p...

    Lihe Liu, Rocío Amorín, Philipe Moriel, Nicolás DiLorenzo in BMC Genomics (2021)

  7. Article

    Open Access

    Histological and transcriptomic analysis of adipose and muscle of dairy calves supplemented with 5-hydroxytryptophan

    In mammals, peripheral serotonin is involved in regulating energy balance. Herein, we characterized the transcriptomic profile and microstructure of adipose and muscle in pre-weaned calves with increased circu...

    Sena L. Field, Marcela G. Marrero, Lihe Liu, Francisco Peñagaricano in Scientific Reports (2021)

  8. Article

    Open Access

    Differential network analysis of bovine muscle reveals changes in gene coexpression patterns in response to changes in maternal nutrition

    Coexpression network analysis is a powerful tool to reveal transcriptional regulatory mechanisms, identify transcription factors, and discover gene functions. It can also be used to investigate changes in coex...

    Lihe Liu, Rocío Amorín, Philipe Moriel, Nicolás DiLorenzo in BMC Genomics (2020)

  9. Article

    Open Access

    Gestational and lactational exposure to gossypol alters the testis transcriptome

    Reproductive capacity can be altered by challenges experienced during critical periods of development, including fetal development and early neonatal life. Gossypol is a polyphenolic compound, commonly found i...

    Helder Louvandini, Patricia S. Corrêa, Rocío Amorín, Lihe Liu, Egon H. Ieda in BMC Genomics (2020)

  10. No Access

    Article

    Effect of yeast polysaccharide on some hematologic parameter and gut morphology in channel catfish (Ictalurus punctatus)

    A study was conducted to investigate the effect of dietary yeast polysaccharides on some hematologic parameters and intestinal morphology of channel catfish. Channel catfish were fed diets containing yeast pol...

    Huiling Zhu, Huiyu Liu, **g Yan, Rui Wang, Lihe Liu in Fish Physiology and Biochemistry (2012)