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Open AccessResearch on the coordinated development of provincial urbanization and carbon emission efficiency of construction industry in China
Energy conservation and emission reduction policies restrict the economic and social development of all countries in the world, and the impact on China, which has low urbanization, is more serious. In the proc...
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A healable, mechanically robust and ultrastretchable ionic conductive elastomer for durably wearable sensor
The ionic conductive elastomers show great promise in multifunctional wearable electronics, but they currently suffer from liquid leakage/evaporation or mechanical compliance. Develo** ionic conductive elast...
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Open AccessComparison of clinical characteristics and disease burden between early- and late-onset type 2 diabetes patients: a population-based cohort study
The clinical characteristics of early-onset type 2 diabetes (T2D) patients are not fully understood. To address this gap, we conducted a cohort study to evaluate clinical characteristics and disease burden in ...
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Open AccessAssociation between dietary vitamin C and abdominal aortic calcification among the US adults
Cardiovascular disease (CVD) is the leading cause of mortality, and vascular calcification has been highly correlated with CVD events. Abdominal aortic calcification (AAC) has been shown to predict subclinical...
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The Effect of Cerebellar rTMS on Modulating Motor Dysfunction in Neurological Disorders: a Systematic Review
The effectiveness of cerebellar repetitive transcranial magnetic stimulation (rTMS) on motor dysfunction in patients with neurological disorders has received increasing attention because of its potential for n...
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Rotator cuff tear reaching the superior half portion of the humeral head causes shoulder abduction malfunction
To examine the biomechanical properties governing posterosuperior rotator cuff (RC) tear progression and dynamic shoulder abduction function, in the absence of excess loading.
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Open AccessData source profile reporting by studies that use routinely collected health data to explore the effects of drug treatment
Routinely collected health data (RCD) are important resource for exploring drug treatment effects. Adequate reporting of data source profiles may increase the credibility of evidence generated from these data....
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Liposomal Doxorubicin: the Sphingomyelin/Cholesterol System Significantly Enhances the Antitumor Efficacy of Doxorubicin
Doxorubicin (DOX) has a cytotoxic effect on many tumor cells; however, its clinical application is limited owing to its strong side effects. Although Doxil® reduces the cardiotoxicity of free DOX, it has also ...
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Open AccessThe use of a technology-assisted and teacher-supervised online discussion platform to promote academic progress in blended embryology courses
Students’ engagement with learning materials and discussions with teachers and peers before and after lectures are among the keys to the successful implementation of blended programs. Mixed results have been r...
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An Application of Tumor-Associated Macrophages as Immunotherapy Targets: Sialic Acid–Modified EPI-Loaded Liposomes Inhibit Breast Cancer Metastasis
Breast cancer metastasis is an important cause of death in patients with breast cancer and is closely related to circulating tumor cells (CTCs) and the metastatic microenvironment. As the most infiltrating imm...
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Antitumor Immunotherapy of Sialic Acid and/or GM1 Modified Coenzyme Q10 Submicron Emulsion
Immunotherapy is a novel therapeutic approach for controlling and killing tumor cells by stimulating or reconstituting the immune system, among which T cells serve as immune targets. Herein, we used coenzyme Q...
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Open AccessReporting of abstracts in studies that used routinely collected data for exploring drug treatment effects: a cross-sectional survey
In recent years, studies that used routinely collected data (RCD), such as electronic medical records and administrative claims, for exploring drug treatment effects, including effectiveness and safety, have b...
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Open AccessUtilization of traditional Chinese medicine in the intensive care unit
Previous studies showed that traditional Chinese medicine (TCM) may be effective for patients with critical conditions. However, the extent to which TCM is used in intensive care units (ICUs) remains less inve...
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Observation and analysis of morphology abnormalities in development of Oryzias melastigma embryos
Fish embryos are widely used as models in toxicology, drug development, and human disease research because of their high sensitivity, observability, and operability, providing the basis for an in-depth underst...
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Westward movement of tertiary education resources along the Belt and Road
Nearly half of the Belt and Road countries are still in the opportunity window of demographic dividend. Based on the experiences of China and many other countries, the improvement of health and education level...
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Open AccessClinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province
The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences betwe...
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Open AccessThe epidemiology and clinical outcomes of ventilator-associated events among 20,769 mechanically ventilated patients at intensive care units: an observational study
Ventilator-associated pneumonia (VAP) is the most common hospital-acquired infection (HAI) in intensive care units (ICUs). Ventilator-associated event (VAE), a more objective definition, has replaced tradition...
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Open AccessModeling of the fibrin agarose plate assay and its application for thrombolytic analysis
The fibrin agarose plate assay is widely used in the detection of thrombolysis efficacy. However, a rigorous mathematical model for analyzing data or comparing activities of different thrombolytics has been ab...
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Improvement of thermostability of recombinant collagen-like protein by incorporating a foldon sequence
Collagen is a popular biomaterial in many specific biological interactions as well as a structural element. In this work, the recombinant collagen-like proteins were synthesized using Escherichia coli expression ...
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Environmental study on a long history of Cu mining in Hubei, central China
