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Article
Optimum test planning for heterogeneous inverse Gaussian processes
The heterogeneous inverse Gaussian (IG) process is one of the most popular and most considered degradation models for highly reliable products. One difficulty with heterogeneous IG processes is the lack of ana...
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Article
Open AccessStructural insight into catalytic mechanism of PET hydrolase
PET hydrolase (PETase), which hydrolyzes polyethylene terephthalate (PET) into soluble building blocks, provides an attractive avenue for the bioconversion of plastics. Here we present the structures of a nove...
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Article
Improving the catalytic performance of a GH11 xylanase by rational protein engineering
XynCDBFV from Neocallimastix patriciarum is among the most effective xylanases and holds great potentials in a wide variety of industrial applications. In the present study, several active site residues were modi...
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Article
Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop
Cellulase 12A from Thermotoga maritima (TmCel12A) is a hyperthermostable β-1,4-endoglucanase. We recently determined the crystal structures of TmCel12A and its complexes with oligosaccharides. Here, by using site...
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Article
Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-β-d-glucanase
1,3-1,4-β-d-Glucanase has been widely used as a feed additive to help non-ruminant animals digest plant fibers, with potential in increasing nutrition turnover rate and reducing sanitary problems. Engineering of ...
