Skip to main content

8 Result(s)

within Biomedicine Remove this filter

and

  1. Article

    Open Access

    ANGPTL3 is a novel HDL component that regulates HDL function

    Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...

    Longyan Yang, Yan Wang, Yongsong Xu, Kun Li, Ruili Yin… in Journal of Translational Medicine (2024)

    Download PDF (2181 KB) View Article

  2. Article

    Open Access

    SGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways

    Although the prognosis for most patients with papillary thyroid cancer (PTC) is good, the present treatment is ineffective for 5–10% patients. Several studies found sodium–glucose cotransporter 2 (SGLT2) inhib...

    Yan Wang, Longyan Yang, Lin Mao, Lijie Zhang, Yingjun Zhu… in Cancer Cell International (2022)

    Download PDF (7835 KB) View Article

  3. No Access

    Chapter

    The Application of Oligosaccharides in Breeding Industry

    As the increasing demand for antibiotic substitution at home and abroad, animal husbandry will face serious challenges. How to ensure the healthy growth of breeding animals in the post-antibiotic era has becom...

    Qingsong Xu, Lunxue Wang, Yuguang Du in Oligosaccharides of Chitin and Chitosan (2019)

  4. No Access

    Article

    The effects of 18β-glycyrrhetinic acid and glycyrrhizin on intestinal absorption of paeoniflorin using the everted rat gut sac model

    Paeoniflorin (PF), the main active component of Shaoyao-Gancao-tang, possesses significantly antinociceptive effects and many other pharmacological activities. However, its poor intestinal absorption results i...

    Rui He, Yongsong Xu, **g**g Peng, Tingting Ma, **g Li… in Journal of Natural Medicines (2017)

  5. No Access

    Article

    Optimization of combinations of ginsenoside-Rg1, ginsenoside-Rb1, evodiamine and rutaecarpine for effective therapy of mouse migraine

    Wuzhuyu decoction (WZYD) is a classic traditional Chinese medicine (TCM) formula. It has been extensively used for treating migraine for thousands of years in TCM. Four potential active ...

    Yanchuan Wu, Xueqiang Pan, Yongsong Xu, Xuran Lu, Shida He… in Journal of Natural Medicines (2016)

  6. No Access

    Article

    Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases

    Neutrophils are early responders and must navigate using spatial cues to arrive at infection sites. Xu and colleagues show that the opposing activities of MAP kinases Erk and p38 govern neutrophil migration.

    **aowen Liu, Bo Ma, Asrar B Malik, Haiyang Tang, Tao Yang, Bo Sun… in Nature Immunology (2012)

  7. No Access

    Article

    Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins

    To kill pathogens, neutrophils must be able to transmigrate into tissues. Xu and colleagues show that the kinase MYLK, by phosphorylating Pyk2, is required for neutrophils to reach sites of infection.

    **gsong Xu, **ao-Pei Gao, Ramaswamy Ramchandran, You-Yang Zhao… in Nature Immunology (2008)

  8. No Access

    Article

    Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

    The longitudinal growth of the skeleton arises from the continuous process of endochondral ossification occurring at the ends of growing long bones. Dwarfism results when this process is disrupted, as in the a...

    Michael C. Naski, Qing Wang, **gsong Xu, David M. Ornitz in Nature Genetics (1996)