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Article
Open AccessPersistence of peripheral CD8 + CD28− T cells indicates a favourable outcome and tumour immunity in first-line HER2-positive metastatic breast cancer
The contradictory role of CD8 + CD28− T cells in tumour immunity has been reported, while their biological and clinical significance in HER2-positive metastatic breast cancer (MBC) is still unknown.
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Article
Open AccessHydroxymethylation hydroxylation of 1,3-diarylpropene through a catalytic diastereoselective Prins reaction: cyclization logic and access to brazilin core
A catalytic diastereoselective Prins reaction for hydroxymethylation and hydroxylation of 1,3-diarylpropene was successfully utilized to prepare various 1,3-dioxanes 7 in 14–88% yields. Take advantage of the synt...
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Article
Open AccessAnalysis of vertical differentiation of vegetation in Taishan World Heritage site based on cloud model
While the forests on Mount Taishan are predominantly man-made, there is a notable vertical variation in vegetation. This study employs the method of cloud model, quantifying uncertainty (fuzziness and randomne...
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Article
Comprehensive analysis of stress-activated protein kinase genes (OsSAPKs) in rice flowering time
The rice SnRK2 members SAPK4, SAPK5, SAPK7 and SAPK10 are positive regulators involved in the regulation of rice flowering, while other single mutants exhibited no effect on rice flowering.
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Article
A novel functional allele of Ehd3 controls flowering time in rice
Rice flowering time determines its geographical distribution and yield traits. As a short-day plant, rice can grow in the northern long-day conditions due to the functional mutations of many photosensitive gen...
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Article
Open AccessEPB41L4A-AS1 is required to maintain basal autophagy to modulates Aβ clearance
Alzheimer’s disease (AD) is the most common neurodegenerative disorder characterized by the deposition of β-amyloid (Aβ) plaques. Aβ is generated from the cleavage of the amyloid precursor protein by β and γ-s...
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Article
Dual-path temporal map optimization for make-up temporal video grounding
Make-up temporal video grounding (MTVG) aims to localize the target video segment, which is semantically related to a sentence describing a make-up activity in a make-up video. Compared with the general video ...
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Article
Selenium-Chitosan Protects Porcine Endometrial Epithelial Cells from Zearalenone-induced Apoptosis via the JNK/SAPK Signaling Pathway
This study was designed to assess whether selenium-chitosan (Se-CTS) can protect porcine endometrial epithelial cells (PEECs) against damage and apoptosis induced by zearalenone (ZEA) via modulating the JNK/SA...
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Article
Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity
Mosquito transmitted viruses are responsible for an increasing burden of human disease. Despite this, little is known about the diversity and ecology of viruses within individual mosquito hosts. Here, using a ...
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Article
Enhancing the mechanical and magnetic properties for low magnetic stainless-steel plates by non-recrystallization hot rolling and solution treatment
Develo** low magnetic stainless-steel plates with high yield strength while ensuring good plasticity, corrosion resistance, and paramagnetism is a tough technical challenge, especially under conditions of li...
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Article
Open AccessJian Gan powder ameliorates immunological liver injury in mice by modulating the gut microbiota and metabolic profiles
Immunological liver injury (ILI) is a common liver disease associated with the microbiota-gut-liver axis. Jian Gan powder (JGP) exhibits both protective and therapeutic effects on hepatitis virus-induced ILI i...
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Article
Open AccessPediatric upper lip myopericytoma: a case report and comprehensive review
Myopericytoma is a rare spindle cell tumor of mesenchymal origin, typically benign, characterized by concentric proliferation of tumor cells around blood vessels within subcutaneous tissue. It primarily occurs...
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Article
Enhancing pile bearing capacity estimation through random forest-based hybridization approach
In civil engineering, the precise determination of pile bearing capacity holds paramount importance in ensuring foundations' safe and efficient design. The primary goal of this study is to develop innovative A...
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Article
Open AccessTick-borne bacterial agents in Hyalomma asiaticum ticks from **njiang Uygur Autonomous Region, Northwest China
Hyalomma ticks are widely distributed in semi-arid zones in Northwest China. They have been reported to harbor a large number of zoonotic pathogens.
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Article
Correction to: Ethically Questionable Negotiation Strategies in South Asia: A Comparative Study of India and Pakistan
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Article
IFree Filter-Based User Positioning for Satellite-Based Augmentation System
Ionospheric storms and scintillation cause great impact on the service performance of single-frequency Satellite-Based Augmentation System (SBAS). On the one hand, conservative estimation method of the ionosph...
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Article
Digital audio tampering detection based on spatio-temporal representation learning of electrical network frequency
The majority of Digital Audio Tampering Detection (DATD) methods, which are based on Electrical Network Frequency (ENF), predominantly concentrate on the static spatial information of ENF. Unfortunately, this ...
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Article
An ingenious construction of porous sodium alginate/TEMPO-oxidized cellulose composite aerogels for efficient adsorption of crystal violet dyes in wastewater
Since caustic dyes are a major component of wastewater used in printing and dyeing, they represent a significant risk to human health. It’s getting harder to get rid of them efficiently. An appealing solution ...
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Article
Open AccessA simple and economic method to modify large organic surfaces for enhancing adhesion and transparent Au/PMMA with high electromagnetic shielding efficiency
This study introduces a simple and cost-effective approach for modifying large organic surfaces, facilitating robust adhesion between Au films and polymethyl methacrylate (PMMA) while retaining transparency to...
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Article
Open AccessANGPTL3 is a novel HDL component that regulates HDL function
Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...
