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  1. Article

    Open Access

    ANGPTL3 is a novel HDL component that regulates HDL function

    Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...

    Longyan Yang, Yan Wang, Yongsong Xu, Kun Li, Ruili Yin… in Journal of Translational Medicine (2024)

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  2. Article

    Open Access

    SGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways

    Although the prognosis for most patients with papillary thyroid cancer (PTC) is good, the present treatment is ineffective for 5–10% patients. Several studies found sodium–glucose cotransporter 2 (SGLT2) inhib...

    Yan Wang, Longyan Yang, Lin Mao, Lijie Zhang, Yingjun Zhu… in Cancer Cell International (2022)

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  3. No Access

    Article

    The effects of 18β-glycyrrhetinic acid and glycyrrhizin on intestinal absorption of paeoniflorin using the everted rat gut sac model

    Paeoniflorin (PF), the main active component of Shaoyao-Gancao-tang, possesses significantly antinociceptive effects and many other pharmacological activities. However, its poor intestinal absorption results i...

    Rui He, Yongsong Xu, **g**g Peng, Tingting Ma, **g Li… in Journal of Natural Medicines (2017)

  4. No Access

    Article

    Optimization of combinations of ginsenoside-Rg1, ginsenoside-Rb1, evodiamine and rutaecarpine for effective therapy of mouse migraine

    Wuzhuyu decoction (WZYD) is a classic traditional Chinese medicine (TCM) formula. It has been extensively used for treating migraine for thousands of years in TCM. Four potential active ...

    Yanchuan Wu, Xueqiang Pan, Yongsong Xu, Xuran Lu, Shida He… in Journal of Natural Medicines (2016)

  5. No Access

    Article

    Synthesis and thermo-sensitive property of star poly(N-isopropylacrylamide) with α -D-glucose-based group

    Polymers containing functional biological activity groups have potential biological application. A new type of initiator (Glu-Br) synthesized by α-D-glucose and excessive 2-bromo-isobutyrlbromide was used to i...

    Yuan Cui, Yongsong Xu, **gpeng Zhang, Qian Duan in Journal of Polymer Research (2016)