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Article
Open AccessANGPTL3 is a novel HDL component that regulates HDL function
Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...
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Article
Open AccessEpigallocatechin-3-gallate ameliorates hepatic damages by relieve FGF21 resistance and promotion of FGF21–AMPK pathway in mice fed a high fat diet
Non-alcoholic fatty liver disease (NAFLD) is considered to be one of the most common chronic liver diseases across worldwide. Epigallocatechin-3-gallate (EGCG) derived from extract of green tea and is well kno...
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Article
Open AccessLipidomic profiling reveals distinct differences in plasma lipid composition in overweight or obese adolescent students
The relationship between dyslipidemia and obesity has been widely reported, but the global lipid profiles associated with the development of obesity still need to be clarified. An investigation into the associ...
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Article
Open AccessmiR-706 inhibits the oxidative stress-induced activation of PKCα/TAOK1 in liver fibrogenesis
Oxidative stress induces the activation of liver fibrogenic cells (myofibroblasts), thus promoting the expression of fibrosis-related genes, leading to hepatic fibrogenesis. MicroRNAs (miRNAs) are a new class ...
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Article
Postconditioning attenuates renal ischemia–reperfusion injury by mobilization of stem cells
We recently showed that reactive oxygen species (ROS) and mitochondrial DNA damage and deletions were attenuated by postconditioning (POC). It is not known, however, whether a population of progenitor cells is...
