178 Result(s)
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Open AccessUpadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2)
Atopic dermatitis (AD) is characterized by intense itch and other symptoms that negatively impact quality of life (QoL). This study evaluates the effect of upadacitinib (an oral selective Janus kinase inhibito...
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Open AccessBoosting thermoelectric performance of single-walled carbon nanotubes-based films through rational triple treatments
Single-walled carbon nanotubes (SWCNTs)-based thermoelectric materials, valued for their flexibility, lightweight, and cost-effectiveness, show promise for wearable thermoelectric devices. However, their therm...
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Open AccessDietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue
The high-protein diet (HPD) has emerged as a potent dietary approach to curb obesity. Peroxisome, a highly malleable organelle, adapts to nutritional changes to maintain homeostasis by remodeling its structure...
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Open AccessCirculating tumor cell-derived exosome–transmitted long non-coding RNA TTN-AS1 can promote the proliferation and migration of cholangiocarcinoma cells
Exosomes assume a pivotal role as essential mediators of intercellular communication within tumor microenvironments. Within this context, long noncoding RNAs (LncRNAs) have been observed to be preferentially s...
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Open AccessDisseminated Cryptococcus neoformans infection involving multiple bones and lung in an immunocompetent patient: a case report
Cryptococcal osteomyelitis is a rare and potentially serious condition, typically encountered in individuals with compromised immune systems. This case underscores the unusual occurrence of disseminated Crypto...
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Open AccessRetrospective analysis of urethral anastomosis with ancillary maneuvers and intraoperative biaxial defect measurements to achieve a tension free guidance system for redo PFUDD treatment
Redo surgery for pelvic fracture urethral distraction defects (PFUDDs) is still a challenge. the long urethral defect makes it difficult while the high tension increase the recurrence rate. Although certain an...
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Open AccessRetraction Note: Digital transformation, green innovation, and carbon emission reduction performance of energy-intensive enterprises
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Open AccessExercise intervention in middle-aged and elderly individuals with insomnia improves sleep and restores connectivity in the motor network
Exercise is a potential treatment to improve sleep quality in middle-aged and elderly individuals. Understanding exercise-induced changes in functional plasticity of brain circuits that underlie improvements i...
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Open AccessC/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription
Acute myeloid leukemia (AML) with biallelic (CEBPAbi) as well as single mutations located in the bZIP region is associated with a favorable prognosis, but the underlying mechanisms are still unclear. Here, we pro...
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Open AccessRETRACTED ARTICLE: Digital transformation, green innovation, and carbon emission reduction performance of energy-intensive enterprises
Digital transformation and green innovation are powerful initiatives to achieve carbon peaking, carbon neutrality targets and high-quality economic development. Using a sample of high energy-consuming listed e...
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Open AccessANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway
Ovarian cancer (OC) has the highest mortality rate among all gynecological malignancies. A hypoxic microenvironment is a common feature of solid tumors, including ovarian cancer, and an important driving facto...
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Open AccessSignificance of relative phase features for shouted and normal speech classification
Shouted and normal speech classification plays an important role in many speech-related applications. The existing works are often based on magnitude-based features and ignore phase-based features, which are d...
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Open AccessCirculating secretoneurin level reflects angiographic coronary collateralization in stable angina patients with chronic total occlusion
To investigate the association between circulating secretoneurin (SN) and angiographic coronary collateralization in stable angina patients with chronic coronary total occlusion (CTO).
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Open AccessThe learning curve for laparoscopic pancreaticoduodenectomy by a proficient laparoscopic surgeon: a retrospective study at a single center
To explore the learning curve of single center laparoscopic pancreaticoduodenectomy (LPD) and evaluate the safety and efficacy of the operation at different stages.
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RETRACTED ARTICLE: Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway
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Open AccessIdentify Landslide Precursors from Time Series InSAR Results
Landslides cause huge human and economic losses globally. Detecting landslide precursors is crucial for disaster prevention. The small baseline subset interferometric synthetic-aperture radar (SBAS-InSAR) has ...
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Open AccessHalloysite-gold core-shell nanosystem synergistically enhances thermal conductivity and mechanical properties to optimize the wear-resistance of a pheonlic-PBO/PTFE textile composite liner
Polymer-textile liner composites have potential applications in aerospace applications for reducing the abrasion damage of moving parts during operation owing to their self-lubrication, light weight, and high ...
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Open AccessTopological structure of complex predictions
Current complex prediction models are the result of fitting deep neural networks, graph convolutional networks or transducers to a set of training data. A key challenge with these models is that they are highl...
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Open AccessDeciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution
The timely onset of female parturition is a critical determinant for pregnancy success. The highly heterogenous maternal decidua has been increasingly recognized as a vital factor in setting the timing of labo...
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Open AccessAge-related promoter-switch regulates Runx1 expression in adult rat hearts
Runt-related transcription factor-1 (RUNX1), a key member of the core-binding factor family of transcription factors, has emerged as a novel therapeutic target for cardiovascular disease. There is an urgent ne...