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Article
Nitrogen addition-driven soil organic carbon stability depends on the fractions of particulate and mineral-associated organic carbon
Nitrogen (N) deposition greatly affects soil carbon (C) fractions, triggering changes in soil organic carbon (SOC) persistence and functionality. However, the responses of soil C fractions to N deposition rema...
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Article
Physicochemical parameters combined with sensory and discriminant regression, for quality and sensory characterization of licorice for both food and medicine
Licorice, as a traditional medicinal and edible plant, exhibits variations in quality and applications due to differences in geographic origin and growth year. However, the intricate and complex relationship b...
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Article
N-cycle gene abundance determination of N mineralization rate following re-afforestation in the Loess Plateau of China
Afforestation effectively improved soil microbial communities and significantly increased soil nitrogen mineralization rate (Rm).
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Article
Open AccessNlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates
Hematopoietic stem and progenitor cells generate all the lineages of blood cells throughout the lifespan of vertebrates. The emergence of hematopoietic stem and progenitor cells is finely tuned by a variety of...
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Article
Open AccessCAS Landslide Dataset: A Large-Scale and Multisensor Dataset for Deep Learning-Based Landslide Detection
In this work, we present the CAS Landslide Dataset, a large-scale and multisensor dataset for deep learning-based landslide detection, developed by the Artificial Intelligence Group at the Institute of Mountai...
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Article
Mitochondrial dysfunction: a new molecular mechanism of intervertebral disc degeneration
Intervertebral disc degeneration (IVDD) is a chronic degenerative orthopedic illness that causes lower back pain as a typical clinical symptom, severely reducing patients' quality of life and work efficiency, ...
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Article
Open AccessCorrection: Generating hematopoietic cells from human pluripotent stem cells: approaches, progress and challenges
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Article
Open AccessGenerating hematopoietic cells from human pluripotent stem cells: approaches, progress and challenges
Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the production of blood cells for clinical application. In two decades, almost all types of blood cells can be successfully ge...
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Article
Reduced adsorption of norfloxacin on UV aging microplastics in anoxic environment
Over recent years, much attention has been paid to aging problem of microplastics and adsorption behavior of antibiotic on microplastics. In this study, four microplastics, including polystyrene (PS), polyprop...
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Article
Open AccessGlia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells
In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to secondary niches where they expand and differentia...
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Article
Open AccessEfficient expansion of rare human circulating hematopoietic stem/progenitor cells in steady-state blood using a polypeptide-forming 3D culture
Although widely applied in treating hematopoietic malignancies, transplantation of hematopoietic stem/progenitor cells (HSPCs) is impeded by HSPC shortage. Whether circulating HSPCs (cHSPCs) in steady-state bl...
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Article
Open Access3D printing of dual-cell delivery titanium alloy scaffolds for improving osseointegration through enhancing angiogenesis and osteogenesis
The repair of large bone defects is a great challenge for orthopedics. Although the development of three-dimensional (3D) printed titanium alloy (Ti6Al4V) implants with optimized the pore structure have effect...
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Article
Open AccessBiomechanical cues as master regulators of hematopoietic stem cell fate
Hematopoietic stem cells (HSCs) perceive both soluble signals and biomechanical inputs from their microenvironment and cells themselves. Emerging as critical regulators of the blood program, biomechanical cues...
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Article
Open AccessDasatinib enhances anti-leukemia efficacy of chimeric antigen receptor T cells by inhibiting cell differentiation and exhaustion
Relapses of CD19-expressing leukemia in patients who achieved initial remission after CART cell treatment have been reported to correlate with poor CART cells persistence. Sustained tonic signaling or strong a...
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Article
Open AccessEnhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells
Decades of efforts have attempted to differentiate the pluripotent stem cells (PSCs) into truly functional hematopoietic stem cells (HSCs), yet the problems of low differentiation efficiency in vitro and poor ...
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Article
A reputation-based cooperative content delivery with parking vehicles in vehicular ad-hoc networks
In recent years, vehicular ad-hoc network (VANET) is getting a growing interest due to its significant function in terms of vehicle information services and vehicular entertainment applications. In particular,...
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Article
Open AccessThe prognostic value of platelet-to-lymphocyte ratio on the long-term renal survival in patients with IgA nephropathy
Platelet-to-lymphocyte ratio (PLR) was established showing the poor prognosis in several diseases, such as malignancies and cardiovascular diseases. But limited study has been conducted about the prognostic va...
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Article
Open AccessCeramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways
Clinical management of triple-negative breast cancer (TNBC) patients remain challenging because of the development of chemo-resistance. Identification of biomarkers for risk stratification of chemo-resistance ...
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Article
Open AccessThe oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation
Isocitrate dehydrogenase (IDH1/2) gene mutations are the most frequently observed mutations in cartilaginous tumors. The mutant IDH causes elevation in the levels of R-enantiomer of 2-hydroxylglutarate (R-2HG)...
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Chapter and Conference Paper
Collaborative Robot Gras** System Based on Gaze Interaction
The bionic robotic arm has the characteristics of high safety, lightweight and portability, which can assist humans in completing various daily activities in life. Based on the research background of human-mac...