2,086 Result(s)
-
Article
Open AccessThe role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance
Relapse in T-cell acute lymphoblastic leukemia (T-ALL) may signify the persistence of leukemia-initiating cells (L-ICs). Ectopic TAL1/LMO expression defines the largest subset of T-ALL, but its role in leukemi...
-
Article
Open AccessIntegrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae)
Herpetospermum pedunculosum (Ser.) C. B. Clarke is a traditional Chinese herbal medicine that heavily relies on the lignans found in its dried ripe seeds (Herpetospermum caudigerum), which have antioxidant and h...
-
Article
Open AccessTreatment of malignant airway obstruction with Y-shape sigma stent loaded with I125 seeds installed via rigid bronchoscopy
To summarize and analyze the safety and efficacy of a Y-shape Sigma stent loaded with I125 in patients with inoperable malignant main airway obstruction.
-
Article
Effect of oxygen concentration on the heat release behaviour of bituminous coal over the complete spontaneous combustion process
The effect of different oxygen concentration conditions on the heat release behaviour of bituminous coal during spontaneous combustion was investigated. Thermal analysis experiments were conducted using differ...
-
Article
Epidemiology, pathogenesis, immune evasion mechanism and vaccine development of porcine Deltacoronavirus
Coronaviruses have been identified as pathogens of gastrointestinal and respiratory diseases in humans and various animal species. In recent years, the global spread of new coronaviruses has had profound influ...
-
Article
Open AccessA Semi-Supervised Learning Framework for Classifying Colorectal Neoplasia Based on the NICE Classification
Labelling medical images is an arduous and costly task that necessitates clinical expertise and large numbers of qualified images. Insufficient samples can lead to underfitting during training and poor perform...
-
Article
Open AccessTargeted metabolomics profiling in pregnancy associated with vitamin D deficiency
Vitamin D deficiency is common in pregnancy, however, its effects has not been fully elucidated. Here, we conducted targeted metabolomics profiling to study the relationship.
-
Article
Open AccessAssociation between viral infection and bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis
Bronchopulmonary dysplasia (BPD) is the most common serious complication of very preterm infants (VPI) or very low birth weight (VLBW) infants. Studies implicate viral infections in etiopathogenesis. The aim o...
-
Article
Open AccessAdditional suture augmentation to anterior cruciate ligament reconstruction with hamstring autografts bring no benefits to clinical results, graft maturation and graft-bone interface healing
From the perspective of graft protection and early rehabilitation during the maturation and remodeling phases of graft healing, suture augmentation (SA) for anterior cruciate ligament reconstruction (ACLR) has...
-
Article
Exploring the effect of stress arousal on the positive emotional design of multimedia learning
Positive emotional design has been shown to have an important impact on multimedia learning. However, before learning multimedia materials, students may inevitably be stressed by external factors such as learn...
-
Article
Open AccessCorrection: Desmoglein-2 Affects Vascular Function in Moyamoya Disease by Interacting with MMP-9 and Influencing PI3K Signaling
-
Article
Open AccessConjunctive encoding of exploratory intentions and spatial information in the hippocampus
The hippocampus creates a cognitive map of the external environment by encoding spatial and self-motion-related information. However, it is unclear whether hippocampal neurons could also incorporate internal c...
-
Article
Design, synthesis and herbicidal activity of novel cyclohexanedione derivations containing pyrazole and pyridine groups as potential HPPD inhibitors
4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27; HPPD) is one of the important target enzymes in the development of herbicides. To discover novel HPPD inhibitors with unique molecular, 39 cyclohexanedione d...
-
Article
Influence of building spatial patterns on wind environment and air pollution dispersion inside an industrial park based on CFD simulation
The “spatial pattern-wind environment-air pollution” within building clusters is closely interconnected, where different spatial pattern parameters may have varying degrees of impact on the wind environment an...
-
Article
Relative importance of altitude shifts with plant and microbial diversity to soil multifunctionality in grasslands of north-western China
Above- and belowground biodiversity determines the capacity of ecosystems to provide multiple functions simultaneously (i.e., multifunctionality), while their relative importance along environmental gradients ...
-
Article
Correction to: A new strategy for groundwater level prediction using a hybrid deep learning model under Ecological Water Replenishment
-
Article
The Diagnostic Value of Carnett’s Test with Chronic Abdominal Pain: A Narrative Review
Chronic abdominal wall pain is a poorly recognized cause of chronic abdominal pain, and patients frequently go misdiagnosed despite a battery of medical tests. The Carnett’s test is a diagnostic tool used to d...
-
Article
Causal effects of blood pressure and the risk of frailty: a bi-directional two-sample Mendelian randomization study
Observational studies have indicated that high blood pressure (BP) may be a risk factor to frailty. However, the causal association between BP and frailty remains not well determined. The purpose of this bi-di...
-
Article
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis
Renal fibrosis is the final pathological change in renal disease, and aging is closely related to renal fibrosis. Mitochondrial dysfunction has been reported to play an important role in aging, but the exact m...
-
Article
OMGD-StarGAN: improvements to boost StarGAN v2 performance
A good image editing model should learn to map the relationships between styles from different domains, cater to the high quality and diversity of the generated images, and be highly scalable across different ...
