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Article
Open AccessSpin disorder control of topological spin texture
Stabilization of topological spin textures in layered magnets has the potential to drive the development of advanced low-dimensional spintronics devices. However, achieving reliable and flexible manipulation o...
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Article
Open AccessANGPTL3 is a novel HDL component that regulates HDL function
Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...
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Article
Open AccessImpairments of GABAergic transmission in hippocampus mediate increased susceptibility of epilepsy in the early stage of Alzheimer’s disease
Patients with Alzheimer’s disease (AD) are often co-morbid with unprovoked seizures, making clinical diagnosis and management difficult. Although it has an important role in both AD and epilepsy, abnormal γ-am...
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Article
Open AccessDesign of an automated robotic microinjection system for batch injection of zebrafish embryos and larvae
This paper presents the design of a vision-based automated robotic microinjection system for batch injection of both zebrafish embryos and larvae. A novel visual recognition algorithm based on an automatic thr...
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Article
Open AccessCAS Landslide Dataset: A Large-Scale and Multisensor Dataset for Deep Learning-Based Landslide Detection
In this work, we present the CAS Landslide Dataset, a large-scale and multisensor dataset for deep learning-based landslide detection, developed by the Artificial Intelligence Group at the Institute of Mountai...
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Article
Open AccessFractional quantum ferroelectricity
For an ordinary ferroelectric, the magnitude of the spontaneous electric polarization is at least one order of magnitude smaller than that resulting from the ionic displacement of the lattice vectors, and the ...
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Article
Open AccessEffect of organic shock loading on anaerobic performance of pumice-reinforced up-flow anaerobic sludge bed for incineration leachate treatment
The research and application of leachate in the treatment of leachate in UASB reactors are increasing, but UASB also has problems such as poor resistance to organic load impact and unstable operation. In order...
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Article
Open AccessThe use of a technology-assisted and teacher-supervised online discussion platform to promote academic progress in blended embryology courses
Students’ engagement with learning materials and discussions with teachers and peers before and after lectures are among the keys to the successful implementation of blended programs. Mixed results have been r...
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Article
Open AccessAnisotropic, biomorphic cellular Si3N4 ceramics with directional well-aligned nanowhisker arrays based on wood-mimetic architectures
Inspired by the transport behavior of water and ions through the aligned channels in trees, we demonstrate a facile, scalable approach for constructing biomorphic cellular Si3N4 ceramic frameworks with well-align...
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Article
Open AccessSGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways
Although the prognosis for most patients with papillary thyroid cancer (PTC) is good, the present treatment is ineffective for 5–10% patients. Several studies found sodium–glucose cotransporter 2 (SGLT2) inhib...
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Article
Open AccessResearch on the degradation of ancient Longquan celadons in the Dalian Island shipwreck
Eleven celadons with different degrees of degradation excavated from the Dalian Island shipwreck of the Yuan Dynasty (1271–1368 AD) were selected, and the degradation mechanism of the ancient porcelain at mari...
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Open AccessCorrosion of Longquan celadons in the marine environment: study on the celadons from the Dalian Island shipwreck of the Yuan Dynasty
The Dalian ( ) Island shipwreck of the Yuan Dynasty (1271–1368 CE) was located in the sea area of **tan ( ), Fujian ( ...
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Article
Open AccessS-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells. Here we describe S-Trimer, a native-...
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Open AccessDesign and testing of a soft parallel robot based on pneumatic artificial muscles for wrist rehabilitation
Wrist rehabilitation is needed to help post-stroke and post-surgery patients recover from wrist fracture or injury. Traditional rehabilitation training is conducted by a therapist in a hospital, which hinders ...
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Article
Open AccessAn inhibitor of apoptosis protein (EsIAP1) from Chinese mitten crab Eriocheir sinensis regulates apoptosis through inhibiting the activity of EsCaspase-3/7-1
Inhibitor of apoptosis proteins (IAPs) maintain the balance between cell proliferation and cell death by inhibiting caspase activities and mediating immune responses. In the present study, a homolog of IAP (de...
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Article
Open AccessPrediction of room-temperature half-metallicity in layered halide double perovskites
Half-metallic ferromagnets (HMFs) that possess intriguing physical properties with completely spin-polarized current are key candidates for high-efficiency spintronic devices. However, HMFs that could simultan...
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Article
Open AccessInterplay between Kitaev interaction and single ion anisotropy in ferromagnetic CrI3 and CrGeTe3 monolayers
Magnetic anisotropy is crucially important for the stabilization of two-dimensional (2D) magnetism, which is rare in nature but highly desirable in spintronics and for advancing fundamental knowledge. Recent w...
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Article
Open AccessAmniotic fluid metabolomics and biochemistry analysis provides novel insights into the diet-regulated foetal growth in a pig model
Foetal loss and intrauterine growth restriction are major problems in mammals, but there are few effective ways in preventing it. Intriguingly, chitosan oligosaccharide (COS), a biomaterial derived from chitos...
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Article
Open AccessRandom rotation survival forest for high dimensional censored data
Recently, rotation forest has been extended to regression and survival analysis problems. However, due to intensive computation incurred by principal component analysis, rotation forest often fails when high-d...
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Article
Open AccessAsymptotic law of limit distribution for fractional Ornstein-Uhlenbeck process
We consider the minimum L 1 ...