498 Result(s)
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Article
SVEN_5003 is a Major Developmental Regulator in Streptomyces venezuelae
Many regulatory genes that affect cellular development in Streptomyces, such as the canonical bld genes, have already been identified. However, in this study, we identified sven_5003 in Streptomyces venezuelae as...
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Article
Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke
Neuronal ferroptosis plays a key role in neurologic deficits post intracerebral hemorrhage (ICH). However, the endogenous regulation of rescuing ferroptotic neurons is largely unexplored. Here, we analyzed the...
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Article
Modification of Microstructural and Fluid Migration of Bituminous Coal by Microwave–LN2 Freeze–Thaw Cycles: Implication for Efficient Recovery of Coalbed Methane
To improve the efficiency of coalbed methane and recoverability of reservoirs, enhanced fracturing technology is usually required to improve the low porosity and permeability status of coal reservoirs. As a fe...
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Open AccessUpadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2)
Atopic dermatitis (AD) is characterized by intense itch and other symptoms that negatively impact quality of life (QoL). This study evaluates the effect of upadacitinib (an oral selective Janus kinase inhibito...
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Constructing on-demand single/multi-color transitioning fabrics with photocatalysis/photothermal-armed deficient semiconductors
On-demand color switching systems that utilize synchronized semiconductor-catalyzed reduction and photothermal-accelerated oxidation in liquid/solid are highly appealing. Herein, on-demand single/multi-color s...
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Article
Cannabidiol Exerts Sedative and Hypnotic Effects in Normal and Insomnia Model Mice Through Activation of 5-HT1A Receptor
Cannabis sativa has been used for improving sleep for long history. Cannabidiol (CBD) has drown much attention as a non-addictive psychoactive component in Cannabis sativa extract. However, the effects of CBD on...
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Open AccessBoosting thermoelectric performance of single-walled carbon nanotubes-based films through rational triple treatments
Single-walled carbon nanotubes (SWCNTs)-based thermoelectric materials, valued for their flexibility, lightweight, and cost-effectiveness, show promise for wearable thermoelectric devices. However, their therm...
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Open AccessDietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue
The high-protein diet (HPD) has emerged as a potent dietary approach to curb obesity. Peroxisome, a highly malleable organelle, adapts to nutritional changes to maintain homeostasis by remodeling its structure...
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Article
Open AccessCirculating tumor cell-derived exosome–transmitted long non-coding RNA TTN-AS1 can promote the proliferation and migration of cholangiocarcinoma cells
Exosomes assume a pivotal role as essential mediators of intercellular communication within tumor microenvironments. Within this context, long noncoding RNAs (LncRNAs) have been observed to be preferentially s...
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Article
AP-1 and SP1 trans-activate the expression of hepatic CYP1A1 and CYP2A6 in the bioactivation of AFB1 in chicken
Dietary exposure to aflatoxin B1 (AFB1) is harmful to the health and performance of domestic animals. The hepatic cytochrome P450s (CYPs), CYP1A1 and CYP2A6, are the primary enzymes responsible for the bioactivat...
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Open AccessDisseminated Cryptococcus neoformans infection involving multiple bones and lung in an immunocompetent patient: a case report
Cryptococcal osteomyelitis is a rare and potentially serious condition, typically encountered in individuals with compromised immune systems. This case underscores the unusual occurrence of disseminated Crypto...
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Article
Open AccessRetrospective analysis of urethral anastomosis with ancillary maneuvers and intraoperative biaxial defect measurements to achieve a tension free guidance system for redo PFUDD treatment
Redo surgery for pelvic fracture urethral distraction defects (PFUDDs) is still a challenge. the long urethral defect makes it difficult while the high tension increase the recurrence rate. Although certain an...
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Article
HIV encephalopathy is contributed by macrophages and microglia
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Article
Study on the mechanism and properties of new polyacrylamide emulsion polymerization with ester as continuous phase
Emulsion polymerization is an effective means of synthesizing high-molecular-weight polymers in order to reduce the consumption of fossil energy. This paper adopts isoamyl octanoate to replace white oil as the...
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Article
Regulating ion transport behaviors toward dendrite-free potassium metal batteries: recent advances and perspectives
With abundant potassium resources and high capacity, potassium metal batteries (PMBs) present a compelling option for the next generation of energy storage technology. However, PMBs suffer from an unstable ano...
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Article
Open AccessRetraction Note: Digital transformation, green innovation, and carbon emission reduction performance of energy-intensive enterprises
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Article
Open AccessExercise intervention in middle-aged and elderly individuals with insomnia improves sleep and restores connectivity in the motor network
Exercise is a potential treatment to improve sleep quality in middle-aged and elderly individuals. Understanding exercise-induced changes in functional plasticity of brain circuits that underlie improvements i...
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Article
Coordination between two cis-elements of WRKY33, bound by the same transcription factor, confers humid adaption in Arabidopsis thaliana
To cope with flooding-induced hypoxia, plants have evolved different strategies. Molecular strategies, such as the N-degron pathway and transcriptional regulation, are known to be crucial for Arabidopsis thaliana
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Article
Open AccessC/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription
Acute myeloid leukemia (AML) with biallelic (CEBPAbi) as well as single mutations located in the bZIP region is associated with a favorable prognosis, but the underlying mechanisms are still unclear. Here, we pro...
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Article
Expression and clinical significance of hypoxia-induced long non-coding RNA TCONS_I2_00001955 in breast cancer
Long non-coding RNAs (lncRNAs) have been found to play important roles in occurrence, development, and metastasis of various tumors. We aimed to screen long non-coding RNAs (lncRNAs) that promote invasion and ...
